Located in the north-central part of Anatolia, Amasya has hosted many civilizations throughout history. The city existed as a major commercial and cultural center during the Byzantine, Seljuk, and Ottoman eras. Many monumental works were gifted by these civilizations to the city, including the Bayezid II Mosque, which was constructed during the Ottoman Empire. In this study, the Bayezid II Mosque was assessed under static and dynamic loads. Results from the static analyses revealed the sections where stress and deformations occurred under static loads. Iron braces were used in these parts to reduce these impacts. Results from the dynamic analyses indicated that the sections of the structure where stresses and deformations have large values are the domes, the minarets, narthex, and the bottom and top points of the columns in the main load-bearing unit. The data derived from this study can serve to guide future restoration efforts.