Association of depression with treatment outcomes in Type 2 Diabetes Mellitus: A cross-sectional study from Karachi, Pakistan

Zuberi, Saman I; Syed, Ehsan Ullah; Bhatti, Junaid

doi:10.1186/1471-244x-11-27

Cited by 41 publications

(39 citation statements)

References 28 publications

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“…[91213] This association was not revealed in our patients; obviously this was related to anorexia originated by depression. This explains the higher rate of physical activity in T2D-depressed patients reported in literature;[914] however, this association was not revealed in our patients.…”

Section: Discussionmentioning

confidence: 72%

Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components

Bensbaa

Agerd

Boujraf

et al. 2014

J Neurosci Rural Pract

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Background:The global prevalence of diabetes is increasing worldwide. In Morocco, diabetes and depression are major public health problems, requiring improvement in their care. Diabetes and depression are associated with morbidity and early mortality. This association contributes to raising the risk of the complications that occur, while causing higher suffering to patients, as also an increased cost toward healthcare.Aim:This study aims to assess the prevalence of depression in patients with type 2 diabetes (T2D), and identify the main risk factors for depression in this category of diabetic patients.Patients and Methods:Type 2 diabetic patients and older than 18 years of age were recruited. The exclusion criteria included being type 1 diabetic, pregnant woman, hospitalized patients, a history of neurological disorders, such as, stroke, infectious episidodes, and history of psychiatric disorders. The individual patient data was collected through individual and confidential interviews lasting 30 minutes, at the end of the diabetology consultation, by the same diabetologist, trained to use the psychometric scales that were needed. The Moroccan–Arabic version of the Beck diagnostic scale of depression was used. Patients assessed with depressive disorders were reviewed in a specialized psychiatric consultation. The statistical analysis was achieved by using SPSS package (version 17). We retained a threshold P value of 0.05.Settings and Design:A cross-sectional study was conducted that included adults with type 2 diabetes. The depression diagnosis was performed using the Arabic version of the Beck Depression scale.Statistical Analysis:We included 142 patients with type 2 diabetes, with an average age of 56.26 years. The prevalence of depression was 33.1%. The risk factors recognized for depression were, lack of social security, hypertension, and a history of type 2 diabetes of more than five years.Results and Conclusions:In this study, we have focused on the frequent association of ‘Type 2 diabetes and depression’ and the risk of mutual aggravation of both pathologies that might require multidisciplinary healthcare, as well as, improvement in the risk factors of depression through improved access to healthcare, with the extension of social security. The stability of the healthcare personnel involved in the treatment of both chronic diseases, including diabetes and hypertension screening, should also be considered for better management of psychiatric complications.

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Section: Discussionmentioning

confidence: 72%

Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components

Bensbaa

Agerd

Boujraf

et al. 2014

J Neurosci Rural Pract

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“…In contrast to previous studies, and in agreement with others, the current study revealed that women had a worse HRQoL than men patients with type 2 diabetes. This difference could be explained by the fact that women have a higher risk of developing cardiovascular disease and depression or anxiety than men. Furthermore, in addition to having greater difficulty in engaging in physical exercise, women usually find themselves overburdened with commitments toward household activities which may lead to a negative physical and psychological impact …”

Section: Discussionmentioning

confidence: 99%

Exploring variables associated with poor health‐related quality of life in patients with type 2 diabetes in Jordan

Jarab

Alefishat

Mukattash

et al. 2018

J Pharm Health Serv Res

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Objective The study aim was to evaluate health‐related quality of life (HRQoL) and to explore factors associated with poor HRQoL in patients with type 2 diabetes in Jordan. Methods The EQ‐5D questionnaire was used to assess HRQoL in outpatients (n = 196) with type 2 diabetic during their clinic appointment at three major Hospitals in Jordan. Sociodemographic and medical data were collected from patient interviews and medical files. Multiple linear regression was performed to build a model with variables associated with poor HRQoL. Key findings The mean score of the total EQ‐5D index of the 196 participants was 0.724. Most of the patients reported ‘some problems’ through the five dimensions, with the highest percentage (46.1%) related to mobility domain. Regression analysis identified women gender (β = −0.252; P < 0.01), duration of diabetes (β = −0.344; P < 0.01) number of medications (β = −0.423; P < 0.01), and insulin therapy (β = −0.205; P < 0.05) as being significantly associated with poor HRQoL. Conclusions The quality of life for patients with type 2 diabetes in Jordan has considerable scope for improvement. Future diabetes management programs should focus on improving HRQoL, with specific attention to be given for women patients, those who have long duration of diabetes, and patients receiving multiple medications or insulin therapy.

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“…There was difference of post prandial glucose between two groups, that was significant higher in case groups (304 vs. 208, p=0.02). This is relevant with previous study which stated depression complicate blood glucose control in metabolic syndrome or diabetes patient 3,4,5,25,26 . There was no correlation between metabolic syndrome component and depression.…”

Section: Introductionmentioning

confidence: 68%

“…About 15% population ever had major depression episode in their life and Note: *significant; Education 1: no education andelementary school, 2: junior and senior high school, bachelor, 3: graduate and post graduate; Occupation 1: Unemployed,house wife, 2: Private, labor, farmer 3: government employment, retired, army, policeman,Income 1:<1 million/month, 2:1-5 million/month, 3:>5 million/month, Marital Status 1: Never married, 2: married, 3: divorce/death spouse 3,4,5 . Depression decreased quality of life 6,7 .…”

Section: Introductionmentioning

confidence: 99%

Type of psychosocial stressor as risk factor of depressive symptom in metabolic syndrome

Fauziyati

Siswanto

Purnomo

et al. 2016

Bangladesh J Med Sci

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Abstract:Metabolic syndrome and depression are two major diseases over the world, which are increasing in prevalence over time. Depression is a major mental health burden over the world. In long time, depression can lead to metabolic syndrome, while metabolic syndrome is a risk factor for developing depression. Metabolic syndrome is a major risk factor for developing cardiovascular disease. Chronic stress induced by psychosocial stressor leads to the development of both metabolic syndrome and depression. Further research is important to identify which type of psychosocial stressor is the risk factor for depressive symptom in patients with metabolic syndrome. The objective of this study is to identify the type of psychosocial stressor which could be the risk factor for depressive symptom. The study design was case control. The case group consisted of metabolic syndrome patients with depressive symptom, while the control group consisted of metabolic syndrome patients without depressive symptom. Metabolic syndrome was diagnosed based on International Diabetes Federation (IDF) criteria. Depressive symptom was measured by Beck Depression Inventory (BDI). Psychosocial stressors were measured by Stressful Life Events (SLE) questionnaire. Dependent variable was depressive symptom, while independent variables were type of psychosocial stressors (finance, work, social relationship, health and housing). Analysis methods that used in this study were independent t test, Pearson/ Spearman correlation analysis, chi square and logistic regression. There were 54 patients in this study, consisted of 24 in case group and 30 in control group. There was no significant difference in most basic characteristics between two groups. There was significant difference of SLE score between two groups. Chi square analysis showed that housing, finance, health, social relationship, and work stressors were risk factors for developing depressive symptom in metabolic syndrome (OR 24.5 (p 0.001); 9.7 (p 0.039); 8.4 (p 0.016); 5.4 (p 0.004); 3.9 (p 0.001), respectively). Demographic factor which also influenced depressive symptom was salary less than 1 million per month (OR 45, p 0.004). According to logistic regression analysis, psychosocial stressors which most influenced the depressive symptom were finance and housing. In conclusion, this study showed that housing, finance, health, social relationship and work stressors were risk factors for developing depressive symptom in metabolic syndrome.

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Association of depression with treatment outcomes in Type 2 Diabetes Mellitus: A cross-sectional study from Karachi, Pakistan

Cited by 41 publications

References 28 publications

Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components

Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components

Exploring variables associated with poor health‐related quality of life in patients with type 2 diabetes in Jordan

Type of psychosocial stressor as risk factor of depressive symptom in metabolic syndrome

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