2019
DOI: 10.18051/jbiomedkes.2019.v2.111-116
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Asupan vitamin B6, B9, B12 memiliki hubungan dengan risiko penyakit kardiovaskular pada lansia

Abstract: LATAR BELAKANGIndonesia akan memasuki periode lansia (aging), dimana 10% penduduk akan berusia 60 tahun ke atas, di tahun 2020. Bertambahnya usia, penyakit tidak menular banyak muncul seperti hipertensi, stroke, dan diabetes melitus (DM). Menurut penelitian yang dilakukan oleh Gugun, asupan gizi atau mikronutrien antara lain asam folat, vitamin B6, dan B12 berpengaruh terhadap terjadinya resiko penyakit kardiovaskular dikarenakan asupan mikronutrien tersebut dapat menurunkan kadar homosistein yang berperan dal… Show more

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Cited by 3 publications
(4 citation statements)
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“…There is moderate to high inadequacy of vitamin A, C, and E due to low fruit and vegetable intake leading to high free-radical and low immune function [32]. The folate deficiency is high in adults and senior adults potentially increasing the risk of anemia and cardiovascular disease [33][34][35]. There is also a high deficiency of vitamin B 12 that is important to improve cognitive function and lower the risk of cardiovascular disease [34][35][36].…”
Section: Nutrient Intakementioning
confidence: 99%
“…There is moderate to high inadequacy of vitamin A, C, and E due to low fruit and vegetable intake leading to high free-radical and low immune function [32]. The folate deficiency is high in adults and senior adults potentially increasing the risk of anemia and cardiovascular disease [33][34][35]. There is also a high deficiency of vitamin B 12 that is important to improve cognitive function and lower the risk of cardiovascular disease [34][35][36].…”
Section: Nutrient Intakementioning
confidence: 99%
“…Salah satu penyebab meningkatnya homosistein adalah defisiensi asam folat. 11,12 Homosistein yang tinggi di dalam darah menyebabkan peningkatan stres oksidatif, gangguan fungsi endotel, dan induksi trombosis. Pada akhirnya akan menginduksi terbentuknya aterosklerosis yang menjadi salah satu faktor penyebab terjadinya PAP.…”
Section: Pembahasanunclassified
“…Hasil penelitian ini tidak sejalan dengan teori yang menyatakan bahwa defisiensi vitamin B6 dapat menjadi salah satu faktor penyebab meningkatnya risiko seseorang menderita PAP dan asupan vitamin B6 harian ditemukan lebih rendah pada penderita PAP. 11,12 Vitamin B6 berperan dalam menurunkan risiko penyakit kardiovaskuler. 14 Peran dari vitamin B6 dalam menurunkan risiko penyakit jantung dan pembuluh darah adalah melalui fungsi koenzimatiknya untuk mendegradasi homosistein melalui jalur transulfurasi.…”
Section: Pembahasanunclassified
“…Folic acid is a water-soluble vitamin and can be produced synthetically. Based on a study, folic acid consumption can reduce the incidence of stroke in hypertensive patients (Akhirul and Chondro 2019) Folate is found naturally in plants, such as dark green leafy vegetables. Folate plays a very important role in pregnancy and childhood for continued cell division and growth because it can be used to synthesize and repair Deoxyribonucleic Acid (DNA) (Listiyana, Mardiana, and Prameswari 2013).…”
Section: Introductionmentioning
confidence: 99%