Biflavonoids from Brazilian pine Araucaria angustifolia as potentials protective agents against DNA damage and lipoperoxidation

Antioxidants extraction from Pinhão ( Araucaria angustifolia (Bertol.) Kuntze) coats and application to zein films

“…Similarly, compounds 10 and 11 (pseudomolecular ions [M−H] − at m/z 865), could be assigned to Btype (epi)catechin trimers. In all instances, the fragmentation patterns were consistent with those expected for such types of compounds, i.e., similar to those observed for proanthocyanidins dimers but with Proanthocyanidins and biflavonoids have been previously described as the most abundant compounds in A. angustifolia (Freitas et al, 2009;Peralta et al, 2016;da Silva et al, 2014;Yamaguchi, Kato, & Di, 2009;Yamaguchi, Vassa, Kato, & Mascio, 2005). Nevertheless, to the best of our knowledge, a detailed characterization of the proanthocyanidin fraction in A. angustifolia seeds has not been previously described.…”

Biological activities and chemical constituents of Araucaria angustifolia : An effort to recover a species threatened by extinction

“…In leaves of A. angustifolia, six main biflavones were identified: amentoflavone, mono-O-methylamentoflavone, di-O-methylamentoflavone, ginkgetin, tri-O-methyl amentoflavone and tetra-O methyl-amentoflavone (Figure 2) (Yamaguchi et al, 2005;Souza et al, 2014). The fraction rich in biflavonoids obtained from the leaves of A. angustifolia showed a greater ability to eliminate the singlet oxygen radical when compared with quercetin and ginkgetin.…”

“…Moreover, at least in two papers (Yamaguchi et al, 2005;Souza et al, 2014) it was observed that, similar to quercetin and rutin, the fraction rich in biflavonoids proved to be able of protecting liposomes against lipid peroxidation induced by ultraviolet (UV) radiation, which is responsible for damage caused to the skin .…”

Chemical Constituents and Biological Activities of Araucaria angustifolia (Bertol.) O. Kuntze: A Review

“…In addition to the powerful chemical characterization of the seeds, other parts of the tree are equally important. Studies have reported that the resin (found in the wood and knots), the dead bark (which is naturally discarded by the tree) and the leaves (needles) retain an intriguing chemical composition with dynamic biological activity [10][11][12][13][14][15][16]. Our group has importantly contributions regarding A. angustifolia biological effects.…”

“…Seccon et al [12] showed that the hydroalcoholic extract from Araucaria dead bark presents a total phenolic content of 64 mg/g of gallic acid equivalents (including 1.85 mg/g of anthocyanin content and 12 mg/g of proanthocyanidin Adapted from Cordenunsi et al [6] and Brazilian Food Composition This article is available in: http://organic-inorganic.imedpub.com/archive.php content) along with the presence of flavonols, mainly quercetin, besides the flavan-3-ols catechin and epicatechin. Biflavonoids (dimeric flavonoids) were identified in A. angustifolia leaves [13][14][15], besides high amounts of proanthocyanidins [15].…”