Blood pressure in prospective population based cohort of newborn and infant twins

Levine, Robert S.; Hennekens, Charles H.; Jesse, Mary Jane

doi:10.1136/bmj.308.6924.298

Cited by 76 publications

(35 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in our study, there was little difference between systolic and diastolic readings between 4 months and 12 months of age, and there was no gender difference. As with other studies using ultrasonic devices, the mean systolic and diastolic readings were lower than those found in our study [21,22].…”

Section: Discussioncontrasting

confidence: 82%

Blood pressure in the first year of life in healthy infants born at term

et al. 2007

View full text Add to dashboard Cite

Neonatal hypertension occurs in up to 2% of neonatal intensive care survivors and in up to 3% of all neonates. Normal blood pressure (BP) measurements are required to diagnose and manage appropriately both hypotension and hypertension in the neonate and infant. The aim of this study was to provide normative BP measurements during the first year of life of healthy infants born at term, using an oscillometric method. Neonates were enrolled from August 2003 to August 2005. Exclusion criteria included: infants of mothers with hypertension or diabetes of any type, use of illicit substances, congenital or chromosomal anomaly, admission to the neonatal intensive care unit or possible sepsis. There were 406 infants enrolled, with 150 children followed at 6 months of age and 118 children at 12 months of age. There were no differences in BP measurements at 6 months or 12 months of age by gender, weight or height. A BP measurement above the 90th percentile on day 2 or at 6 months was not predictive of a BP above the 90th percentile at 12 months of age. Higher systolic and diastolic measurements at 6 months and 12 months were found, in comparison to those in previous studies using ultrasonic devices. The findings of this study provide normative BP values for infants during their first year of life, using the oscillometric method, the most frequently used method in paediatric, neonatal intensive care and emergency departments.

show abstract

Section: Discussioncontrasting

confidence: 82%

Blood pressure in the first year of life in healthy infants born at term

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Barker et al [11]and others [12, 13, 14, 15]have reported strong associations between fetal growth and hypertension, type 2 diabetes mellitus, and ischaemic heart disease in adult life. These potential long-term consequences of changes in intrauterine growth, and the fact that optimal fetal growth is a good predictor of infancy and childhood development, emphasise the importance of examining not only the teratogenic risk but also fetal growth abnormalities and perinatal effects associated with drug exposure during pregnancy.…”

Section: Introductionmentioning

confidence: 99%

A Population-Based Prescription Study of Asthma Drugs during Pregnancy: Changing the Intensity of Asthma Therapy and Perinatal Outcomes

et al. 2001

View full text Add to dashboard Cite

Background: Among the goals of gestational asthma, therapy is optimisation of pulmonary function. According to the US Food and Drug Administration, no asthma drugs can be considered ‘safe’ during pregnancy. Fear of adverse fetal effects may thus lead to restrictive use of asthma drugs during pregnancy, and no population-based studies concerning gestational asthma therapy exist. Objectives: To examine whether asthma drugs or changing intensity of asthma therapy during pregnancy was associated with deviations from expected values of gestational age, birth weight, length at birth, or malformations. Methods: The Birth Registry was used to identify all 15,756 primiparous women who gave birth in the County of North Jutland between 1991 and 1996. According to the North Jutland Prescription Database, 303 of these women received prescriptions for asthma drugs during pregnancy. Women who did not purchase any prescription drugs during pregnancy constituted the reference group. Conclusion: Women who received prescriptions for asthma drugs during pregnancy gave birth to infants with birth weight and length at birth within the expected limits. Reducing intensity of asthma treatment during pregnancy was associated with lower birth weight and length at birth. This may indicate that pregnant women chose to discontinue therapy although their disease severity justifies continuation of treatment. However, analyses did not take into account important clinical variables, and results could also be due to confounding factors or chance.

show abstract

“…Twins, therefore, would be expected to have a greater risk of diseases that are associated with lower birth weight, such as coronary heart disease, hypertension and diabetes. However, epidemiological studies in twins have produced conflicting results (8,30,31,39,40,53,60,63).…”

mentioning

confidence: 99%

Effects of twinning, birth size, and postnatal growth on glucose tolerance and hypothalamic-pituitary-adrenal function in postpubertal sheep

Bloomfield

Oliver²,

Harding³

2007

American Journal of Physiology-Endocrinology and Metabolism

View full text Add to dashboard Cite

Bloomfield FH, Oliver MH, Harding JE. Effects of twinning, birth size, and postnatal growth on glucose tolerance and hypothalamic-pituitary-adrenal function in postpubertal sheep. Am J Physiol Endocrinol Metab 292: E231-E237, 2007. First published August 29, 2006; doi:10.1152/ajpendo.00210.2006.-Low birth weight is associated with postnatal physiological changes, including impaired glucose tolerance and increased cortisol secretion, that may predispose to disease in adulthood. Twins are born lighter than singletons, but there are conflicting data regarding the association between birth weight and postnatal physiology in twins. We studied glucose tolerance and ACTH and cortisol responses to a combined corticotropin-releasing hormone and arginine vasopressin (CRH ϩ AVP) challenge in postpubertal female twin (n ϭ 7 twin pairs) and singleton (n ϭ 13) sheep from the same flock. There were no differences in glucose tolerance between twins and singletons and no association with birth weight. Twins had a greater ACTH (P Ͻ 0.05), but not cortisol, response to CRH ϩ AVP than singletons. ACTH area under the curve was inversely related to birth weight in both singletons [R 2 ϭ 0.31, P ϭ 0.05; Ϫ8,311 (SD 3,736) pg ⅐ min ⅐ ml Ϫ1 ⅐ kg Ϫ1 ] and twins (R 2 ϭ 0.49); in twins, this was due to the within-twin pair rather than the betweentwin pair coefficient in the regression analysis [P ϭ 0.02, Ϫ26,856 (9,806) vs. P ϭ 0.1, 8,619 (4,950) pg ⅐ min ⅐ ml Ϫ1 ⅐ kg Ϫ1 ]. We conclude that the reduced fetal growth in twins has postnatal consequences for hypothalamic-pituitary-adrenal function and that this is determined by factors specific to the fetus (within-twin pair) rather than by shared maternal factors (between-twin pair). Studies investigating the associations between fetal growth and postnatal outcomes in twins benefit from an appropriate singleton control group and from analyses evaluating the contribution from both between-and within-pair coefficients in twins.

show abstract

Blood pressure in prospective population based cohort of newborn and infant twins

Cited by 76 publications

References 23 publications

Blood pressure in the first year of life in healthy infants born at term

Blood pressure in the first year of life in healthy infants born at term

A Population-Based Prescription Study of Asthma Drugs during Pregnancy: Changing the Intensity of Asthma Therapy and Perinatal Outcomes

Effects of twinning, birth size, and postnatal growth on glucose tolerance and hypothalamic-pituitary-adrenal function in postpubertal sheep

Contact Info

Product

Resources

About