2018
DOI: 10.1016/j.bcp.2018.02.021
|View full text |Cite
|
Sign up to set email alerts
|

BMP-2 induces angiogenesis by provoking integrin α6 expression in human endothelial progenitor cells

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
37
0

Year Published

2018
2018
2024
2024

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 38 publications
(38 citation statements)
references
References 49 publications
1
37
0
Order By: Relevance
“…As previously reported, LIPUS enhances angiogenesis by increasing VEGF after acute myocardial infarction (39). Additionally, BMP-2 treatment stimulated angiogenesis in human endothelial progenitor cells (40). The incorporation of either BMP-2 or VEGF inside porous scaffolds has been demonstrated to induce both angiogenesis and osteogenesis in a previous study (41).…”
Section: Discussionsupporting
confidence: 54%
“…As previously reported, LIPUS enhances angiogenesis by increasing VEGF after acute myocardial infarction (39). Additionally, BMP-2 treatment stimulated angiogenesis in human endothelial progenitor cells (40). The incorporation of either BMP-2 or VEGF inside porous scaffolds has been demonstrated to induce both angiogenesis and osteogenesis in a previous study (41).…”
Section: Discussionsupporting
confidence: 54%
“…Interestingly, it was reported that RUNX-2 is a component of the genetic program that modulate the expression of VEGF during endochondral bone formation (Zelzer et al, 2001). Furthermore, BMP-2 was found to be able to promote in vitro angiogenesis in human endothelial progenitor cells (Chen et al, 2018) and BMP-2 treatment enhanced VEGFA expression in adipose stem cells grown on biphasic calcium phosphate (Overman et al, 2013). In addition, BMP-4 increased the secretion of VEGF in adult retinal pigment epithelium-19 and in osteoblast-like MC3T3-E1 cells (Kozawa et al, 2001; Vogt et al, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, chondromodulin secreted from the cartilage tissue filling the holes in 75TCP inhibited angiogenesis and preserved cartilage tissue in 75TCP. In addition, since BMP-2 has been reported to be involved in cell aggregation and angiogenesis26,27, if the concentration of BMP-2 is low, so is the capacity for bone formation induced by angiogenesis. Therefore, 75TCP with a low concentration of BMP-2 is advantageous for cartilage formation.…”
Section: Discussionmentioning
confidence: 99%