Cardiovascular diseases in the population of industrial towns and environmental factors

Ибраева, Л. К.; Ажиметова, Г. Н.; Аманбекова, А. У.; Bakirova, R. E.

doi:10.17116/terarkh201587176-78

Cited by 4 publications

(2 citation statements)

References 3 publications

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“…Morbidity rate of circulatory system diseases (CSD) in Kazakhstan continues to grow and mortality rate of CSD continues to be the main cause of general population mortality among all existing disease classes [1], [2]. In industrial regions of Central Kazakhstan, the development of CSD, among which 75% are arterial hypertension, can be influenced by environmental factors [3]. The metabolic syndrome (MetS) contributes significantly to cardiovascular risk development, with abdominal obesity and hypertension being the leading components [4].…”

Section: Introductionmentioning

confidence: 99%

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Койчубеков¹,

Sorokina²,

Korshukov³

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Morbidity rate of circulatory system diseases (CSD) in Kazakhstan continues to grow and the metabolic syndrome (MetS) contributes significantly to cardiovascular risk development. It was known that MetS altered autonomic nervous system (ANS) by decreasing parasympathetic activity and global heart rate variability (HRV), at the same time, the decrease in sympathetic modulation is unclear. Studies investigated associations between anxiety and MetS disorders are rather controversial. Research findings of the MetS influence on health-related quality of life (HRQoL) were also contradictory. The above-mentioned justifies the necessity of research to clarify and deepen the MetS etiology and pathogenesis, as well as to improve its diagnostics efficiency and treatment. AIM: The research goals were to study psychophysiological status and HRQoL in individuals with MetS living in Central Kazakhstan. MATERIALS AND METHODS: Three hundred MetS patients were examined in Karaganda city clinical hospital. Statistical methods and spectral analysis of HRV, simple visual-motor reaction (SVMR), the Spielberger State-Trait Anxiety Inventory, and the Lüscher color test were used. SF-36 questionnaire was used for HRQoL assessment. RESULTS: General decrease in the activity of both sympathetic and parasympathetic branches of ANS was observed in MetS patients. More than half of the examined MetS patients have had a high level of trait anxiety. Most MetS patients have had a low level of the central nervous system (CNS) functional activity. MetS patients are active both in physical and social spheres. Bodily pain syndrome greatly influences MetS patients’ life quality. The patients evaluate their health level as being low. CONCLUSION: Individuals with MetS living in Central Kazakhstan had decreased activity of ANS, prevalence of inhibition processes in CNS, high level of trait anxiety, and bodily pain syndrome affecting life quality.

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Section: Introductionmentioning

confidence: 99%

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Койчубеков¹,

Sorokina²,

Korshukov³

et al. 2020

Open Access Maced J Med Sci

View full text Add to dashboard Cite

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“…In addition to usual risk factors for ischemic heart disease such as age, gender, smoking, obesity, physical inactivity, and lipid status, some environmental factors may also play a role in its development following long-term exposure to them [2][3][4][5]. For instance, it has been previously suggested that hard drinking water -and in particular high magnesium intake -protect against cardiovascular disease (CVD) [6].…”

mentioning

confidence: 99%

Calcium and Magnesium in Drinking Water as Risk Factors for Ischemic Heart Disease

Stevanović¹,

Nikolic²,

Ilic³

2017

Pol. J. Environ. Stud.

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Medical and hygienic assessment of influence of nitrates from decentralized water sources on cardiovascular and circulation systems morbidity

Lototska-Dudyk

Лотоцька

Stanko

2020

AML

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Aim. To analyze the levels of nitrate pollution of decentralized water supply sources in the settlements of Lviv region, and to investigate their influence on the formation of morbidity of the cardiovascular and circulation system among the adult population of the region. Materials and Methods. The study was conducted according to the results of monitoring the nitrate content (mg / dm3) in the decentralized water supply sources for the period of 2012-2018 and the morbidity of the cardiovascular and circulation system of the adult population of 20 districts of Lviv region during 2012-2016. The assessment of health hazards for the adult population of Lviv region from consumption of nitrate-contaminated drinking water was carried out in accordance with the risk assessment methodology based on the calculated hazard coefficients (HQ). The results were processed by traditional methods of variation statistics using licensed computer programs Microsoft Excel and Statistica 10.0. Results and Discussion. The laboratory survey covered 2212 (2012) - 2468 (2018) sources of decentralized water supply in Lviv region. There is a clear tendency of increase in the level of nitrate contamination of the drinking water. Excessive nitrate content was found in 18.6-21.7% of individual sources, 9.9-10.5% of public wells and 12.6-13.3% of public captures. The highest concentrations and the highest percentage of excesses were registered in Mykolaiv, Zhovkva, Zolochiv, and Pustomyty districts, and the smallest of excess nitrates was recorded in Turka, Sambir and Staro-Sambir districts. The average excess nitrate content in the most polluted areas was in the range of 3.3-8.0 MAC, which corresponds to concentrations at 165-400 mg/dm3. The highest rates of cardiovascular morbidity and circulatory system were registered in areas where the population uses mainly decentralized water sources and cases were recorded of significant excess of nitrates in drinking water. The statistical analysis found positive correlation connections between the development of ischemia (moderate, r=0.49, p<0.05), angina pectoris (average, r=0.77, p<0.05), and hypertension (severe, r=0.99, p <0.05) and nitrate content in the drinking water. The determination coefficients were 23.08%, 59.58% and 98.01%, respectively. According to the results of the regression analysis, an adequate mathematical model was constructed to predict the probable development of this pathology among the adult population of the region. An assessment of the health hazard for adults consuming drinking water contaminated with nitrates indicates a threat of increased non-infection morbidity, including that of cardiovascular and circulation system, namely an increase in the average (HQ 1-5) risk of nitrates at 1.8-5.0 MAC to high (HQ 5-10) - at their concentration of 5.9-8.0 MAC. Conclusions. The solution to the problem of reducing nitrate pollution of drinking water should be included amongthe most important issues not only in the field of environmental protection, but also the protection of public health. Improving the environment will help reduce the load on the healthcare system in terms of preventing and treating cardiovascular disease. Keywords: nitrates, drinking water, cardiovascular diseases, diseases of the circulatory system

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Cardiovascular diseases in the population of industrial towns and environmental factors

Cited by 4 publications

References 3 publications

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

Calcium and Magnesium in Drinking Water as Risk Factors for Ischemic Heart Disease

Medical and hygienic assessment of influence of nitrates from decentralized water sources on cardiovascular and circulation systems morbidity

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