Cationic starch iodophores

Abstract

Cross‐linked cationic starches N‐(2‐hydroxyl)propyl‐3‐trimethyl ammonium starch chloride (CQS chloride), N‐(2‐hydroxyl)propyl‐3‐trimethyl ammonium starch iodide (CQS iodide), and N‐(2‐hydroxyl)propyl‐3‐trimethyl ammonium starch iodide–iodine (CQS triiodide) with the degree of substitution (DS) according to cationic groups from 0.04 to 0.62, as well as cross‐linked starch–iodine complexes were synthesized and tested as potential antibacterial agents. Cationic starch iodine derivatives were obtained during ion exchange reaction between CQS chloride and iodide or iodide–iodine anions in aqueous solutions. CQSDS≤0.3 chloride can form several types of iodine complexes, such as the blue amylose–iodine inclusion complex and ionic CQS+I−·(I2)m complex (m ≥ 1). The antibacterial activity of modified starches–iodine samples against different pathogenic bacterial cultures and contaminated water microorganisms was evaluated. CQS chloride and CQS iodide were found to be bacteriostatic. A strong antibacterial activity was characteristic of CQS triiodides in which molecular iodine is present in both ionic and inclusion complexes. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

Effect of Poly(Vinyl Pyrrolidone) on Iodine Release from Acrylate‐Endcapped Urethane‐Based Poly(Ethylene Glycol) Hydrogels as Antibacterial Wound Dressing

“…The weight ratio of KI:I 2 is 1:1.576, similar to the ratio used in the Fixanal iodine standard. [ 26 ] The solution was prepared in four different concentrations as follows. Series 1 (1%): 357.35 mg KI + 226.82 mg I 2 in 50 mL ultrapure H 2 O Series 2 (0.2%): 6 mL of series 1 + 24 mL ultrapure H 2 O Series 3 (0.05%): 1.5 mL of series 1 + 28.5 mL ultrapure H 2 O Series 4 (0.01%): 300 µl of series 1 + 29.7 mL ultrapure H 2 O …”

“…The weight ratio of KI:I 2 is 1:1.576, similar to the ratio used in the Fixanal iodine standard. [26] The solution was prepared in four different concentrations as follows.…”

Polymeric Iodophors: Preparation, Properties, and Biomedical Applications

“…Crosslinked starch derivatives obtained in reactions with epichlorohydrin or 2,3-epoxypropyltrimethylammonium chloride [ 2 ] showed high absorption of iodine anions in solutions. Iodine complexes were obtained with the crosslinked cationic starch derivatives N -(2-hydroxyl)propyl-3-trimethylammonium starch chloride and N -(2-hydroxyl)propyl-3-trimethammonium starch iodide [ 48 ]. Ion exchange reactions between the starch derivatives and iodine yielded ionic complexes, which displayed high antibacterial activity towards pathogenic microorganisms from polluted water.…”

Thiolated Ligand-Functionalized MoS2 Nanosheets for Peroxidase-like Activities

“…A large number of infectious diseases can be terminated by proper application of the disinfectant agents, which restrain and prevent the expansion of harmful microorganisms including bacteria, fungi, and viruses . Traditionally, several antimicrobials have been used to control bacterial infection, namely, numerous antibiotics, halogen-based compounds such as N -halamine polymers, different iodophors, quaternary ammonium ion-based compounds, and various metal ions. , Despite all these efforts, these materials are suffering from several limitations such as cost-effectiveness, environmental issues, efficiency, and so forth. Moreover, the excess use of antibiotics causes a rapid increase in multidrug resistance in bacteria, which makes antibiotics therapeutically abortive .…”