Cellulose‐Based Substrate for SERS‐Promoted Histamine Picomolar Detection in Beverages

Abstract

Histamine is a biogenic amine (BA) playing an important physiological role in human body, even though the assumption of high histamine amount from food and beverages can cause health diseases such as, for example, cutaneous allergy, headache and nausea. In fact, histamine can be present in foods and beverages as the result of microbial metabolism induced by temperatures and storage conditions, so histamine levels are commonly used as an indicator of food safety and quality. In the present contribution, the possibility to detect low concentration of histamine by Surface Enhanced Raman Spectroscopy (SERS) by using silver nanoparticles (AgNPs)-cellulose hybrid substrate has been proposed. An easy procedure for the fabrication of the hybrid supports was developed and SERS effect at different AgNPs amounts was tested. The developed systems allowed detecting histamine down to 10-12 M in aqueous solutions. SERS substrates have been tested directly on two different kinds of commercial white wines, the first one stored in tetra pack and the other one in glass bottles without any pre-treatment procedure. Histamine concentrations in the real samples were obtained by recording the corresponding Raman spectra and confirmed by means of conventional HPLC analysis.[a] Dr.

Strong histamine torsion Raman spectrum enables direct, rapid, and ultrasensitive detection of allergic diseases

“…Surface-enhanced Raman scattering (SERS) is a useful tool to achieve high-precision detection of small molecules ( Giancane et al., 2016 ; Vander Ende et al., 2019 ). Determination of histamine concentration in food by SERS in the high-frequency side (>200 cm −1 ) has been reported recently ( Bettini et al., 2019 ; Huynh et al., 2020 ). However, the detection limit is higher than 1 × 10 −6 g/L and therefore the method can only be used for detecting histamine in food ( Filipec et al., 2021 ; Gao et al., 2015 ; Janči et al., 2017 ; Xie et al., 2017 ).…”

Biomimetic Nanoparticles Based Surface Plasmon Resonance Biosensors for Histamine Detection in Foods

“…Biogenic amines are nitrogenous compounds formed by carboxylation of amino acids or amination and transamination of aldehydes and ketones . The most common foodborne biogenic amine is histamine . Histamine is an organic nitrogen compound which was first described in 1910 by Dale and Laidlaw .…”

“…[1] The most common foodborne biogenic amine is histamine. [2,3] Histamine is an organic nitrogen compound which was first described in 1910 by Dale and Laidlaw. [4] It is mostly seen in protein-rich foods and fermented foods.…”

Facile Bacterial Cellulose Nanofibrillation for the Development of a Plasmonic Paper Sensor

“…With the assistance of amidoxime groups, Au nanoparticles were successfully in situ hydrothermally grown on BC nanofibers by Chen et al for catalyst production . A novel avenue can be built through nanofibrillation methods and optimized NPs immobilization for effective SERS hotspots creation. , …”

“…22 A novel avenue can be built through nanofibrillation methods and optimized NPs immobilization for effective SERS hotspots creation. 23,24 One potentially exploited biodegradable BC-based material is nata de coco (NDC), a very popular food product, typically prepared in the form of a thick jelly, simply prepared by the fermentation of coconut juice, mostly using Acetobacter xylinum. 25,26 In tropical countries like Indonesia, the Philippines, Vietnam, and other Southeast Asian countries, NDC is widely produced not only by high-scale industries but in home industry and is marketed with a considerably cheap price; therefore, it can be potentially exploited as a new generation of green-synthesized thin-film material.…”