Change in elastic modulus of bovine dentine with exposure to a calcium hydroxide paste

MTA versus Ca(OH)2 in apexification of non-vital immature permanent teeth: a randomized clinical trial comparison

“…Furthermore, the organization of the collagen fibrils and hydroxyapatite crystals is different between the root dentine and the coronal dentine [17] that might cause differences in the elastic behaviour in response to exposure to the CH paste. These variations of elastic modulus between coronal and root dentine could explain that CH may lead to an increased risk of crown-root fracture [18]. In the present study, the loss of 26 % of the teeth treated with CH, due to cervical fracture (not apical fracture), supports this theory.…”

Attachment and proliferation of dental pulp stem cells on dentine treated with different regenerative endodontic protocols

“…One possible hypothesis that can explain the adverse effects of Ca(OH) 2 on DPSC proliferation despite its noncytotoxic nature is that Ca(OH) 2 can significantly change the physio‐mechanical properties of surface dentine (Kawamoto et al . , Yassen et al . ), which may cause unfavourable interactions between DPSC and the brittle dentine surface.…”

Chlorhexidine Prevents Root Dentine Mineral Loss and Fracture Caused by Calcium Hydroxide over Time

“…As used by Kawamoto et al, the bovine model used in the present study is a biological model already consolidated in the literature, as it provides a better standardization of the dentin age, it is easy to obtain teeth in good condition, and it shows less variability in organic/inorganic composition than human teeth [31]. …”