Change of arterial stiffness values in different treatment regimens in menopausal women

Салов, И. А.; Tolstov, S. N.; Karagezyan, K.M.; Ребров, А П

doi:10.20953/1726-1678-2018-3-25-32

Cited by 3 publications

(2 citation statements)

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“…Однако, как отмечают A. Scuteri et al [21], у женщин в постменопаузальный период либо после хирургической/химической кастрации наблюдается прогрессирование изменений в сосудистой стенке. Также некоторые авторы описывают редукцию утолщения артериальной стенки у женщин в период постменопаузы на фоне длительной заместительной гормонотерапии [20]. Можно сделать предположение о том, что именно гормональные факторы лежат в основе выраженных изменений длины висцеральных артерий у женщин пожилого возраста.…”

Section: клинические исследованияunclassified

Comparative characteristics of the morphometric parameters of the abdominal part of aorta and its unpaired branches in the age and sex aspects

Gaivoronsky¹,

Гайворонский²,

Быков³

et al. 2019

Bulletin of the Russian Military Medical Academy

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Computer tomograms of the abdominal part of the aorta and its unpaired branches of adults belonging to three age groups are analyzed: the first, the second mature, and the elderly. It has been established that individual morphometric parameters of the abdominal part of the aorta and its unpaired branches in men and women significantly change with age. It is proved that the diameter of the aorta at different levels significantly increases with age from the first mature age to the elderly by an average of 5 mm. In addition, in men, the length of the abdominal aorta, celiac trunk and main trunk of the superior mesenteric artery do not change with age. In women, the length of the celiac trunk increases with age by 5,9 mm, the length of the main trunk of the superior mesenteric artery - by 17 mm. It can be assumed that this fact is due to the structural features of the connective tissue structures of the arterial wall in women, and, in particular, the elastic framework. The angle of discharge of the celiac trunk in men changes unevenly with age - in the second period of mature age, there is a statistically significant decrease on average of 12,3°, then in old age an increase of 15°. Moreover, in women, the values of this indicator vary more evenly. The angles of discharge of other vessels did not show a clear age dependence, since this parameter is largely due to the constitutional features. The aorto-mesenteric distance changes with age only in women. In old age, it is on average 4,4 mm larger than in the first period of mature age. In general, a number of morphometric parameters of the abdominal part of the aorta and its unpaired branches significantly changes with age. The findings are important for endovascular interventions.

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Section: клинические исследованияunclassified

Comparative characteristics of the morphometric parameters of the abdominal part of aorta and its unpaired branches in the age and sex aspects

Gaivoronsky¹,

Гайворонский²,

Быков³

et al. 2019

Bulletin of the Russian Military Medical Academy

View full text Add to dashboard Cite

show abstract

“…Как отмечают Scuteri et al [17], у женщин в постменопаузальный период либо после хирургической и(или) химической кастрации наблюдается прогрессирование изменений в сосудистой стенке. Также некоторые авторы описывают редукцию утолщения артериальной стенки у женщин в период постменопаузы на фоне длительной заместительной гормонотерапии [18]. Можно сделать предположения, что именно гормональные факторы лежат в основе выраженных изменений длины висцеральных артерий у женщин пожилого возраста.…”

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The Comparative Characteristics of Age, Sexual and Typological Morphometric Parameters of Unpaired Branches of the Abdominal Aorta of Adults According Computed Tomography

et al. 2019

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The rapid development of transplantation, endovascular and minimally invasive surgery necessitates a detailed study of the structural features of the vessels of the abdominal cavity. The purpose of the study is the characteristics of the morphometric parameters of the abdominal aorta and its unpaired branches in men and women at different ages and depending on the body type. The analysis of 266 computer tomograms of the abdominal part of aorta and its unpaired branches was carried out in adult men women divided into three age groups (first and second periods of mature age and elderly age), as well as into three groups according to the Pinier index (asthenic, normosthenic and hypersthenic body types). It was established that individual morphometric parameters of the abdominal part of aorta and its unpaired branches in men and women significantly change with age. It is proved that the diameter of the aorta at various levels significantly increases with age from the first mature to the elderly age by an average of 5 mm. However, in men, the length of the abdominal aorta, celiac trunk and main trunk of the superior mesenteric artery does not change with age. In women, the length of the celiac trunk increases with age at 5.9 mm, the length of the main trunk of the superior mesenteric artery - at 17 mm. The angle of discharge of the celiac trunk in men changes unevenly with age - in the second period of mature age, there is a statistically significant decrease by an average to 12.3°, then in old age an increase to 15°. Moreover, in women, the values of this indicator vary more evenly. The angles of discharge of other vessels did not show a clear age dependence, since this parameter is largely due to the constitutional features. The aorto-mesenteric distance changes with age only in women. In elderly age, it is on average 4.4 mm larger than in the first period of mature age. It was also found that there are significant differences between constitutional types identified using the Pinier index in the overwhelming majority of the morphometric parameters studied. The obtained information has a significant clinical importance, since it will allow objectifying the diagnostic criteria of various vascular syndromes and minimizing the risk of endovascular interventions.

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The use of menopausal hormone therapy in women at high cardiovascular risk

Mironova

Козиолова

2022

Arter. gipertenz.

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The review article presents the stages of the use of menopausal hormone therapy (MHT) from the standpoint of primary and secondary prevention of the risk of developing coronary heart disease (CHD) and deaths. Based on the data obtained, a number of guidelines and statement documents have been updated to reflect the need to comply with the “time hypothesis” in the appointment of MHT in order to improve the prognosis. The arguments of the possible use of MHT are shown both in the primary prevention of cardiovascular diseases in women with cardiovascular risk factors, and in patients with a history of coronary artery disease, myocardial infarctions, with the development of chronic heart failure and atrial fibrillation. In 2021, a proposal was put forward to determine the choice of MHT depending on the cardiovascular risk groups (CVR). However, such an approach to the choice of MHT excludes the personification and individualization of the possibility of using this method of treatment in the presence of certain factors of low, intermediate CVR, such as arterial hypertension, hypercholesterolemia, type 2 diabetes mellitus and others, especially with their good control. Therefore, the adoption of clinical decisions on the use of MHT in conditions of high CVR and the presence of individual clinically significant risk factors should be carried out by a multidisciplinary team, which will exclude both unmotivated prohibitions and appointments in the presence of contraindications.

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Change of arterial stiffness values in different treatment regimens in menopausal women

Cited by 3 publications

References 0 publications

Comparative characteristics of the morphometric parameters of the abdominal part of aorta and its unpaired branches in the age and sex aspects

Comparative characteristics of the morphometric parameters of the abdominal part of aorta and its unpaired branches in the age and sex aspects

The Comparative Characteristics of Age, Sexual and Typological Morphometric Parameters of Unpaired Branches of the Abdominal Aorta of Adults According Computed Tomography

The use of menopausal hormone therapy in women at high cardiovascular risk

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