Chemical composition and antimicrobial activities of leaves of sweet basil (Ocimum basilicum L.) herb

Gebrehiwot, Hadush; Bachetti, Rakesh Kumar; Dekebo, Aman

doi:10.18203/2319-2003.ijbcp20150858

Cited by 21 publications

(13 citation statements)

References 18 publications

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“…The obtained data indicated that the OBLP contain high amount of total phenolics and flavonoids compounds in concentration of 39.62 mg GAE/g and 3.84 mg QE/ml respectively and some of the predominant components of the volatile oil were, linalool, farnesene, terpineol, cineole, bisabolol and eugenol in concentration of 5.21, 25.23, 6.03, 2.82, 7.42 and 4.8 respectively. These results showed some variation in the types and concentrations of the chemical compounds than the previously reported by many researchers (Ma andLe, 2019 andGebrehiwot et al, 2015), which can be largely attributed to the differences in experimental conditions, age, plant genetic difference, local climate and seasonal variations.…”

Section: Discussionsupporting

confidence: 55%

Impact of Ocimum basilicum leaves powder on immune response of chicken vaccinated against Newcastle Disease Virus

Mohamed

elaziz

2020

Egyptian Journal of Agricultural Research

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In this research, we study the effect of adding the Ocimum basilicum leaves powder (OBLP), as broilers chicken feed additive and study its effects on the innate and adaptive immune responses as well as the antioxidant effects in broilers vaccinated with Newcastle disease virus (NDV) vaccine. A total of 100 one-day old broiler were randomly divided into 4 equal groups, the first group (G1) was served as normal control group, the second group (G2) was served as vaccination control group. Groups 3 (G3) and 4 (G4) fed 0.5% and 1% OBLP in diets, respectively, and vaccinated against NDV. The obtained results showed that the adding of OBLP to diets improved the broilers innate immune response which resulted in significant increases in peripheral blood monocyte cells phagocytic activity, lysozyme levels and lymphoid organs / body weight ratios. Adaptive immune response has also been improved as the hemagglutination inhibition (HI) antibody titers against NDV vaccine in G3 and G4 reached the peak earlier, declined slowly and gave significantly higher titer in G4 than other groups at the end of the experiment. The antioxidant effects of OBLP were evident particularly by using high concentration of OBLP as the serum catalase enzyme (CAT) levels were significantly increased whereas malondialdehyde (MDA) were significantly reduced. It could be concluded that the use of OBLP as a feed additive can boost the innate and adaptive immune response to NDV vaccination and improve the antioxidant activity of broilers in a dose dependent manner.

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Section: Discussionsupporting

confidence: 55%

Impact of Ocimum basilicum leaves powder on immune response of chicken vaccinated against Newcastle Disease Virus

Mohamed

elaziz

2020

Egyptian Journal of Agricultural Research

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“…In our study, various extracts recorded inhibition against E. coli and S. aureus in agar well diffusion method. Gebrehiwot et al [53] showed that hydrodistilled oil of O. basilicum has antimicrobial activity against E. coli and S. aureus in paper disc diffusion method. But the crude extracts (chloroform:methanol = 1:1) at concentration of 10 and 20 µL, did not recorded activity against the tested microorganisms.…”

Section: Resultsmentioning

confidence: 99%

Comparative Antimicrobial Study of Different Parts of Ocimum americanum L., O. basilicum L. and O. sanctum L. in Comparison to Standard Antibiotics Collected from Dibrugarh, Assam

Chetia

Saikia

Upadhyaya³

et al. 2021

J. Sci. Res.

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Lamiaceae members are commonly used in ethno-medicinal practices of our country. The in vitro antibacterial and antifungal activity of various solvents extracts of different aerial parts of Ocimum americanum L., O. basilicum L. and O. sanctum L. wereassessed on standard bacterial and fungal strains using standard laboratory methods. Extracts from O. americanum have inhibitory activity against B. subtilis, B. cereus and S. aureus.Acetone extracts of O. basilicum and O. sanctum were found to be more potent being capable of exerting significant inhibitory activities against majority of the bacteria investigated. Acetone extract of young inflorescence of O. americanum showed highest antibacterial activity against B. cereus (14±1mm) which was also higher (10±1mm) than the inhibition of standard Clotrimazole (10mcg). Hot petroleum ether extract of mature leaves of O. basilicum showed highest activity against E. coli (16±2mm) which was also higher than the inhibition ofAmpicillin, Streptomycitin, Erythromycin.Petroleum ether extract of young leaves of O. sanctum recorded highest inhibition against P. vulgaris (20±2mm). Presence of tannins, flavonoids, saponins, phenols in all the parts of the plants. Use of different parts instead of using whole plant will help in sustainable management of these medicinal plants.

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“…The ethanolic extract was concentrated by using a rotary evaporator at temperature 40°C. 13 Crude ethanolic extract of O. basilicum was further partitioned according to increasing polarity into nhexane, chloroform and ethyl acetate fraction. Separating funnel was used for further successive partitioning by three solvents in order of increasing polarity, first by n-hexane, second by chloroform and third by ethyl acetate.…”

Section: E T H O D O L O G Ymentioning

confidence: 99%

Antimicrobial activity by solvents extracted from Ocimum basilicum herb against multidrug resistant gram negative rods.

Ikram

Saleem

Imran

et al. 2021

J Islamabad Med Dental Coll

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ABSTRACT: Background: Failure of treatment with antibiotics occurs due to increase in number of Multidrug resistant gram negative bacteria, worldwide. The objective of this study was to find out the antimicrobial activity of crude ethanolic extract and its further three fractions by Ocimum basilicum leaves against multi drug resistant gram negative rods. Material and Methods: This descriptive study was conducted in the Department of Microbiology, University of Health Sciences, Lahore from 1st july 2016 to 30th june 2017. Total 80 multidrug resistant gram negative rods were included in this study. Agar dilution method was performed to determine MIC of crude ethanolic extract and different fractions i-e n-hexane, chloroform and ethyl acetate of Ocimum basilicum leaves against multidrug resistant gram negative rods i-e ESBLs and carbapenemase producers. Muti-inoculater was used for inoculation. Results: The mean MICs of crude ethanolic extract, n-hexane fraction, chloroform fraction, and ethyl acetate fraction of Ocimum basilicum against ESBLs were 100.0±8.00, 168.13±8.00, 176.88±8.00 41.75±8.00 respectively. Similarly, the mean MICs of crude ethanolic extract, n-hexane fraction, chloroform fraction, and ethyl acetate fraction of Ocimum basilicum against carbapenemase producers were 77.50±8.00, 113.75±8.00, 132.50±8.00 and 29.50±8.00 respectively. Conclusions: Ethyl acetate fraction and crude ethanolic extract from leaves of Ocimum basilicum showed good antibacterial effectiveness against ESBLs and carbapenem resistant organisms than other fractions. This finding may also promote the effective use of O. basilicum herb and its components in modern medicine.

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Chemical composition and antimicrobial activities of leaves of sweet basil (Ocimum basilicum L.) herb

Cited by 21 publications

References 18 publications

Impact of Ocimum basilicum leaves powder on immune response of chicken vaccinated against Newcastle Disease Virus

Impact of Ocimum basilicum leaves powder on immune response of chicken vaccinated against Newcastle Disease Virus

Comparative Antimicrobial Study of Different Parts of <i>Ocimum americanum</i> L., <i>O. basilicum</i> L. and <i>O. sanctum</i> L. in Comparison to Standard Antibiotics Collected from Dibrugarh, Assam

Antimicrobial activity by solvents extracted from Ocimum basilicum herb against multidrug resistant gram negative rods.

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