ChemInform Abstract: Two New Flavone Glycosides from the Leaves of Argyreia speciosa Convolvulaceae.

Abstract

Two New Flavone Glycosides from the Leaves of Argyreia speciosa Convolvulaceae.-The isolation and structural characterization of the title compounds ( I) and (II), both of potential medical applicability, is described. -(AHMAD, M.; JAIN, N.; SHAFIULLAH; KHAN, M. S.; ILYAS, M.; J.

Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats

“…et al, 2002), wound healing (Kartik et al, 2003), antimicrobial, (Shukla et al, 1999), immunomodulatory (Gokhale et al, 2003), nootropic activity (Joshi et al, 2007) and flower possesses antidiarrheal activity (Rao et al, 2004). Phytochemical screening of the plant has shown the presence of lipids, flavonoids, triterpenes and phenylpropanoids (Chandler and Hooper, 1979;Batra and Mehta, 1985;Khan et al, 1992;Ahmad and Jain, 1993). The pathophysiology of gastric ulcer has generally focused on imbalance between aggressive and protective factors in the stomach, such as acid-pepsin secretion, mucosal barrier, mucus secretion, blood flow, cellular regeneration, prostaglandins and epidermal growth factors (Lima et al, 2006).…”

Argyreia speciosa (Linn. f.) sweet: A comprehensive review

“…[ 18 19 ] Two flavone glycosides characterized as 7, 8, 3’,4’,5’-pentahydroxyflavone, 5-O-α-L-rhamnopyranoside and 7, 8, 3’,4’,5’-pentahydroxyflavone 5-O-β-D-glucopyranoside were reported from leaves. [ 20 ] A triterpene reported from leaves was friedelanol, 5-O-β-D-glucopyranoside. [ 21 ]…”

Callusing, Cell suspension culture and Secondary Metabolites Production in Argyreia nervosa (Burm. F.) Bojer

“…Extraction of the leaves with 90% methanol led to the isolation of the flavonoids, quercetin and kaemperol together with the latter's glycoside kaemperol-3-o-l-rhamnopyranoside (Khan et al, 1992). Two new flavone glycosides characterized as 7,8,3',4',5'-pentahydroxyflavone5-o-α-lrhamnopyranoside and 7,8,3',4',5'-pentahydroxyflavone5-o-α-l-glucopyranoside were also reported from leaves (Ahmad et al, 1993). The hexane extract of the root yielded tetradecanyl palminate, 5, 8-oxidotetracosan-10-one (Rani and Shukla, 1997) and two novel aryl esters characterized as stigmasteryl p-hydroxycinnamate and hexadecanyl phydroxycinnmate along with scopoletin (Shrivastava and Shukla, 1998).…”