Clinical characteristics of Korean patients with new-onset diabetes presenting with diabetic ketoacidosis

Kim, Mee Kyoung; Lee, Seung Hwan; Kim, Ji Hoon; Lee, Jee In; Kim, Ji Hyun; Jang, Eun Hee; Yoon, Kun‐Ho; Lee, Kwang Woo; Song, Ki‐Ho

doi:10.1016/j.diabres.2009.04.017

Cited by 18 publications

(17 citation statements)

References 16 publications

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“…Regarding the prevalence of KP‐T2D, the notion of a low prevalence of KP‐T2D among Asians may need to be altered. Similar to a previous study conducted in Korea, in which 42% of new‐onset KP‐T2D patients in all new‐onset diabetes patients presented with DKA , 35% of new‐onset diabetic subjects who were admitted to the emergency room presenting with DKA had T2D (A−β+) in this study. However, one must carefully bear in mind that the numbers for KP‐T2D seem to show it to be an extremely rare occurrence, as the incidence of DKA is uncommon in Korean subjects with T2D .…”

Section: Discussionsupporting

confidence: 88%

“…However, one must carefully bear in mind that the numbers for KP‐T2D seem to show it to be an extremely rare occurrence, as the incidence of DKA is uncommon in Korean subjects with T2D . In contrast to previous studies that reported incidences for the A+β+ phenotype of 7.7 % and nearly 11% in Koreans and other ethnicities , respectively, no subjects fulfilled the A+β+ phenotype in this study. In this regard, we postulated that there might be an autoimmune heterogeneity in Korean patients with new‐onset KPD.…”

Section: Discussioncontrasting

confidence: 85%

“…The present study based on the Aβ classification (autoimmunity and β‐cell secretory capacity) for classification of the types or forms of diabetes demonstrated the clinical characteristics of new‐onset KPD patients presenting with DKA in a Korean population. This study uncovered four main findings: first, KP‐T2D was shown to commonly occur (35%) in subjects with new‐onset diabetes presenting with DKA in Korea but DKA rarely occurred in established T2D. Second, this study showed that no patients fulfilled the criteria of KPD‐T2A (A+β+), which might reflect characteristics of atypical T1D or latent autoimmune diabetes in adults.…”

Section: Discussionmentioning

confidence: 73%

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Clinical characteristics and insulin independence of Koreans with new‐onset type 2 diabetes presenting with diabetic ketoacidosis

Seok

Jung²,

et al. 2013

Diabetes Metabolism Res

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 85%

Section: Discussionmentioning

confidence: 73%

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Clinical characteristics and insulin independence of Koreans with new‐onset type 2 diabetes presenting with diabetic ketoacidosis

Seok

Jung²,

et al. 2013

Diabetes Metabolism Res

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“…Nonetheless, the previous decade has seen an expansion in rates of ketosis in type 2 diabetes mellitus (T 2 DM). Numerous researchers have discovered that patients with T 2 DM were helpless to ketosis or ketoacidosis under extraordinary hyperglycemia [3][4]. It is currently perceived that a few patients with type 2 diabetes may likewise give DK or diabetic ketoacidosis (DKA).…”

Section: Introductionmentioning

confidence: 99%

The Influencing Factors Associated with Ketosis-Prone Type 2 Diabetes Mellitus: A Syndrome of Diabetes Mellitus

Karim¹,

Syeda²

2018

IJDE

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Ketosis-prone diabetes or KPD is an intermediate form of diabetes and is a widespread syndrome. To review the influencing factors of ketosis in type 2 diabetes (T 2 DK), All patients of ketosis with type 2 diabetes are studied under single entity as the method. In this review, we described the current state of knowledge in regard to Ethnicity, age, sex, family history, infection, obesity, Dyslipidemia, and Hyperglycemia is associated as the influencing factors in Ketosis-Prone Type 2 Diabetes Mellitus.

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“…According to a recent study, the number of DKA cases in adults has rapidly increased over the previous 20 years [4]. Lee et al [1] reported that poor glycemic control is the most common factor for DKA and In Western countries, the incidence of DKA is relatively high, ranging from 4.6 to 8.0 cases per 1,000 patients with diabetes [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Clinical and Laboratory Characteristics of Pediatric Diabetic Ketoacidosis: A Single-Center Study

et al. 2017

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Background: Diabetic ketoacidosis (DKA) is an acute complication of pediatric type 1 diabetes mellitus (T1DM). We aimed to determine the risk factors and clinical characteristics of children and adolescents with DKA. Methods: We retrospectively evaluated 59 episodes of DKA in 43 patients who were hospitalized for DKA between January 2006 and December 2015. DKA was classified as mild, moderate, or severe, according to patient history of DKA. The clinical and laboratory characteristics of these subgroups were compared. Results: The average patient age was 11.98 ± 4.40 years (range, 1.3~17.9 years). Moderate episodes were the most common, with 21 episodes (35.6%), followed by 19 severe (32.2%) and 19 mild episodes (32.2%). Significant differences were observed between the subgroups regarding their characteristics of aggravated. Severe DKA episodes were more often observed during the winter season. Recurrent DKA cases were determined in 31 episodes (52.5%) who were significantly older, had higher body mass index, and lower serum C-peptide levels than the newly diagnosed DKA group. Female patients experienced severe and moderate cases more frequently (P = 0.041), which included two deaths. Only blood glucoseCorresponding author: Min Sun Kim Department of Pediatrics, Chonbuk National University Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju 54907, Korea, E-mail: children@jbnu.ac.kr Received: Feb. 20, 2017; Revised: Jun. 5, 2017; Accepted: Jul. 18, 2017 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Clinical characteristics of Korean patients with new-onset diabetes presenting with diabetic ketoacidosis

Cited by 18 publications

References 16 publications

Clinical characteristics and insulin independence of Koreans with new‐onset type 2 diabetes presenting with diabetic ketoacidosis

Clinical characteristics and insulin independence of Koreans with new‐onset type 2 diabetes presenting with diabetic ketoacidosis

The Influencing Factors Associated with Ketosis-Prone Type 2 Diabetes Mellitus: A Syndrome of Diabetes Mellitus

Clinical and Laboratory Characteristics of Pediatric Diabetic Ketoacidosis: A Single-Center Study

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