Clinical complications of biodegradable screws for ligament injuries

Ramos, Daisy M.; Dhandapani, Ramya; Subramanian, Anuradha; Sethuraman, Swaminathan; Kumbar, Sangamesh G.

doi:10.1016/j.msec.2019.110423

Cited by 42 publications

(19 citation statements)

References 58 publications

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“…The screws made from this material provided the same fixation strength as titanium screws [ 32 ]. Another synthetic polymer Poly-l-lactic (PLLA) is notable for its gradual degradation and thanks to that is applicable in orthopedics for anterior cruciate ligament reconstruction, ankle fracture treatment or meniscus injury therapy [ 33 , 34 ]. Bio-absorbable screws made from copolymer PLLA/PGA are suitable, e.g., for fixation of osteochondritis dissecans lesions [ 35 ].…”

Section: Indications and Materials For Biodegradable Implants In Orth...mentioning

confidence: 99%

Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications

Modrák

Trebuňová

Balogová

et al. 2023

JFB

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The goal of this review is to map the current state of biodegradable materials that are used in tissue engineering for a variety of applications. At the beginning, the paper briefly identifies typical clinical indications in orthopedics for the use of biodegradable implants. Subsequently, the most frequent groups of biodegradable materials are identified, classified, and analyzed. To this end, a bibliometric analysis was applied to evaluate the evolution of the scientific literature in selected topics of the subject. The special focus of this study is on polymeric biodegradable materials that have been widely used for tissue engineering and regenerative medicine. Moreover, to outline current research trends and future research directions in this area, selected smart biodegradable materials are characterized, categorized, and discussed. Finally, pertinent conclusions regarding the applicability of biodegradable materials are drawn and recommendations for future research are suggested to drive this line of research forward.

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Section: Indications and Materials For Biodegradable Implants In Orth...mentioning

confidence: 99%

Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications

Modrák

Trebuňová

Balogová

et al. 2023

JFB

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show abstract

“…Gore-Tex™ is representative of PTFE artificial ligaments. The root cause for implant failure was believed to be poor biocompatibility of PTFE as host organizations completely failed to grow into the prosthesis [ 53 , 54 ]. Compared with carbon fiber and PTFE, PET possesses satisfying mechanical properties but also biocompatibility thus considered the most promising in artificial ligament fabrication.…”

Section: Strategies For Promotion Of Artificial Ligament Bioactivitymentioning

confidence: 99%

Current strategies for enhancement of the bioactivity of artificial ligaments: A mini-review

Wang

et al. 2022

Journal of Orthopaedic Translation

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“…Conventional orthopaedic screws are made of stainless steel or titanium that are strong, ductile (Liu and Shin, 2019), fatigue-resistant (Gupta et al , 2020) and highly biocompatible (Ratner, 2019). However, due to the high stiffness and high strength of metallic screws, they may cause stress corrosion (Agarwal et al , 2021), stress-shielding effect (Hanawa, 2019), tear and wear in the neighbouring tissues (Ramos et al , 2020). Further, strong integration at the bone–screw interface by sharp threads and soft bony tissues complicates the post-operative revision surgery while removing the metallic screws (Gupta and Pandey, 2016).…”

Section: Introductionmentioning

confidence: 99%

Mechanical and biological behaviour of additive manufactured biomimetic biodegradable orthopaedic cortical screws

Agarwal

Gupta

Singh

2022

RPJ

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Purpose The complications caused by metallic orthopaedic bone screws like stress-shielding effect, screw loosening, screw migration, higher density difference, painful reoperation and revision surgery for screw extraction can be overcome with the bioabsorbable bone screws. This study aims to use additive manufacturing (AM) technology to fabricate orthopaedic biodegradable cortical screws to reduce the bone-screw-related-complications. Design/methodology/approach The fused filament fabrication technology (FFFT)-based AM technique is used to fabricate orthopaedic cortical screws. The influence of various process parameters like infill pattern, infill percentage, layer height, wall thickness and different biological solutions were observed on the compressive strength and degradation behaviour of cortical screws. Findings The porous lattice structures in cortical screws using the rapid prototyping technique were found to be better as porous screws can enhance bone growth and accelerate the osseointegration process with sufficient mechanical strength. The compressive strength and degradation rate of the screw is highly dependent on process parameters used during the fabrication of the screw. The compressive strength of screw is inversely proportional to the degradation rate of the cortical screw. Research limitations/implications The present study is focused on cortical screws. Further different orthopaedic screws can be modified with the use of different rapid prototyping techniques. Originality/value The use of rapid prototyping techniques for patient-specific bone screw designs is scantly reported. This study uses FFFT-based AM technique to fabricate various infill patterns and porosity of cortical screws to enhance the design of orthopaedic cortical screws.

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Clinical complications of biodegradable screws for ligament injuries

Cited by 42 publications

References 58 publications

Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications

Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications

Current strategies for enhancement of the bioactivity of artificial ligaments: A mini-review

Mechanical and biological behaviour of additive manufactured biomimetic biodegradable orthopaedic cortical screws

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