Clinical efficacy of Shodhana Karma and Shamana Karma in Mandala Kushtha (Psoriasis)

Abstract

In India an estimated 0.8% of the population is suffering from Psoriasis. It is a papulo-squamous disorder of the skin, characterized by sharply defined erythemato-squamous lesions. It is chronic and is well known for its course of remissions and exacerbations. The exact etiology is still unknown. This condition is comparable with Mandala Kushtha in Ayurvedic system of medicine. Shodhana procedures are reliable to control the disease. Forty patients, fulfilling the inclusion criteria, were selected and randomly divided into four groups with 10 patients in each group. In Group A, Vamana and Virechana was administered once during the trial period. In Group B, Vamana and Virechana followed by Dermo-care in the dose of 5 g twice a day for the period of 2 months. In Group C, only Dermo-care was administered. In Group D, Tab. Neotrexate (Methotrexate) 7.5 mg/week was given under the supervision of dermatologist. Marked improvement was observed in 10% of the patients in Group B. Moderate improvement was observed in 20% of the patients in Group A, 90% in Group B, and 80% in Group D. Mild improvement was observed in 80% of the patients in Group A, 100% in Group C, and 20% in Group D.

Purva Rupeeyam of bhela indriya sthana-an explorative study

“…Important factors for the manifestation of cardiac cachexia (hrudrogena krusha) include reduction in food intake, gastrointestinal abnormalities, immunological and neuro-hormonal activation and an imbalance between anabolic and catabolic processes. 45 'Praswidyate cha kandumaan --kushtena sa vinashyati' (Verse 7) 4 According to the above verse, 'the patient who sweats excessively (praswidyate), has much of an itching constantly (kandumaan), consume foods that are contrary or allergic (viruddha ahara) and doesn't regularly take purgative measures (avirechana sheelashcha) will get destroyed (vinashyati) by that skin disease (kushta)'. In Ayurveda all skin diseases are categorized under 'Kushtha'.…”

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“…Important factors for the manifestation of cardiac cachexia (hrudrogena krusha) include reduction in food intake, gastrointestinal abnormalities, immunological and neuro-hormonal activation and an imbalance between anabolic and catabolic processes. 45…”

Analytical Study of Kushthaghna Dravyas on the Basis of Rasadi Properties and Doshaghanta From Bhavprakash Nighantu

“…Haritaki, Aragvadhphal, Amalaki, Bhallatakphal, Karveer, Saptaparna, Khadir, Nimba, Guduchi, Adulasa, Parad, Gandhak, Loha, Abhrak, Shilajet, Guggul, Chitrak, Kutaki, Tamra, Javasa, Nimba Vicharchika 14,16,18,28,33 Kutaki, Indrayav, Guggul, Guduchi, Bruhati, Eranda, Snuhi, Patha, Haritaki, Amalaki, Nimba, Khadir, Aragvadh, Kushta, Tuttha, Gandhak, Hartal, Bhringraj, Abhrak Shitapitta 15,31 Pippali,Haritaki, Amalaki, Guggul Sidhma and Dadru 17,38 Chakramarda, Karaj, Gunja, Ghandhak Eka-Kushta 19,21,37 Bhallatak, Haritaki, Amalaki, Pippali, Manjishta, Tuttha, Chitraka, Bakuchi, Loha, Bhringaraj, Guduchi, Bramhi, Shankhapushpi, Jatamansi, Parada, Gandhak, Abhrak, Shilajit, Guggul, Kutaki, Tamra, Aragvadha, Khadir, Nagkeshar, Nimba, Adulasa, Patha, Kushta, Kutaja, Danti, Arka, Karvver, Hartal, Kalihari, Chakramarda, Saptaparna, Snuhi Mandal Kushta 20 Aragvadha, Haritaki, Kutaki, Eranda, Bakuchi, Chitrak, Amalaki, Guduchi, Mandukparni, Guggul, Shilajit, Gandhak, Loha, Suvarnamakshik, Vipadika 23 Sarjak, Manjishtha, Tuttha, Parada, Gandhaka, Laksha, Gunja, Bhrungaraj Kacchu 24 Khadir, Haritaki, Amalaki, Saptaparna, Nimba, Gandhak Yuvan Pidika 25,27 Kushta, Jatamansi, Guggul, Karpoor, Madanphala, Kutaj Darunaka 26 Gunja, Bhringaraj Shushka Vicharchika 28 Haritaki, Amalaki, Chitraka, Kutaki, Pippali, Guduchi, Adulasa, Kushta, Loha, Abhraka, Tamra, Arka Antiviral effect 29 Kirat Pama w.s.r to Scabies 30,36 Khadira, Haritaki, Amalaki, Nimba, Guduchi, Adulasa, Manjishta, Amalaki, Haritaki, Gandhak Shwitra 35,32 Tuttha, Bakuchi, Chitraka, Tulasi…”