“…Similarly, it is likely that the reported anti-inflammatory effects of lidocaine 17,18,19 , in addition to its perceived prokinetic effects 2 , also contributed to the high frequency with which this drug was used, both intra-and postoperatively. Furthermore, in addition to inflammation, pain is recognised as an important risk factor for POI in both humans and horses 1,2,6,9,12,19 . The specific reasons why flunixin was the preferred nonsteroidal anti-inflammatory drug (NSAIDs) remain uncertain; however, its reportedly greater potency against the systemic effects of endotoxaemia 17 , compared with other NSAIDs, may be a contributing factor in light of the respondents perception that endotoxaemia was "quite important" as a risk factor for the development of POI.…”