Clinical range of neonatal rotavirus gastroenteritis.

Dearlove, Joanna; Latham, P; Dearlove, Bethany L.; Pearl, K N; Thomson, Anne; Lewis, IanC.

doi:10.1136/bmj.286.6376.1473

Cited by 55 publications

(31 citation statements)

References 5 publications

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“…Severe complications of rotavirus infection, such as bloody diarrhoea associated with necrotising enterocolitis (NEC) and bowel perforation, have been described (25,26,29). Even though they have not yet been fully elucidated, several factors were associated with the pathogenesis of the disease (30).…”

Section: Discussionmentioning

confidence: 99%

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Nirwati

Hakim

Aminah³

et al. 2017

MJMS

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Background: Rotavirus is an important cause of severe diarrhoea in children. The aims of this study were to identify the rotavirus strains that cause diarrhoea in children in Yogyakarta and to determine the association between rotavirus positivity and its clinical manifestations.Methods: Clinical data and stool samples were collected from children hospitalised at Kodya Yogyakarta Hospital, Indonesia. Rotavirus was detected in stool samples using an enzyme immunoassay (EIA), which was followed by genotyping using reverse transcriptase polymerase chain reaction (RT-PCR). Electropherotyping was performed for the rotavirus-positive samples.Results: In total, 104 cases were included in the study, 57 (54.8%) of which were rotavirus-positive. Based on a multiple logistic regression analysis, age group, vomiting and stool mucous were associated with rotavirus positivity. Most of the 56 samples subjected to genotyping were classified as G1 (80.36%) and P[8] (69.64%) genotypes. The genotype combination G1P[8] was identified as the most prevalent strain (66.07%). Of the 19 samples subjected to electropherotyping, 17 G1 isolates and 1 G3 isolate had long patterns, and 1 G1 isolate had a short pattern.Conclusion: G1P[8] was the most dominant strain of rotavirus causing diarrhoea in children in Yogyakarta. Age group, vomiting and stool mucous were associated with rotavirus positivity.

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Section: Discussionmentioning

confidence: 99%

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Nirwati

Hakim

Aminah³

et al. 2017

MJMS

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“…This is not a classic presentation for preterm NEC and yet these patients do require surgery, have necrotic bowel and have very similar laboratory data. [55][56][57][58] Outcomes for viral enteritis in ELBW and VLBW neonates are surprisingly better than with preterm NEC with regard to the need for surgery and mortality, making it imperative that we differentiate between the two diseases in our prospective trials. 59,60 How to accomplish this is open to debate.…”

Section: Viral Enteritis Of Infancymentioning

confidence: 99%

Emerging trends in acquired neonatal intestinal disease: is it time to abandon Bell's criteria?

et al. 2007

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In the last decade, it has become increasingly clear that necrotizing enterocolitis (NEC) is neither a uniform nor a well-defined disease entity. There are many factors that are forcing this unwelcome realization upon the neonatal and pediatric surgery communities. In the course of this manuscript we will review the history and the physical findings of the disparate etiologies of acquired neonatal intestinal diseases (ANIDs), some which do lead to the common final pathology of NEC and some which do not. New guidelines for distinguishing between ANIDs will also be suggested. (2007) Keywords: necrotizing enterocolitis; spontaneous intestinal perforation; neonate; intestine; premature; diagnosis A brief history of clinical NEC research in the presurfactant era During the late 1970s, necrotizing enterocolitis (NEC) was most commonly seen in preterm infants >30 weeks of gestation. Journal of Perinatology

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“…These findings were consistent with those reported previously by Dearlove et al, i.e., that smaller and sicker babies who stay in hospital longer are more likely to acquire RV infections. 11 The present study also indicated that the clinical manifestations of RV gastroenteritis in this age group were significantly different between those with CA and HA infections, as well as between term and preterm infants. Generally, most CA cases were term babies; term babies more often presented with fever and watery stools, which is a picture similar to that seen in elder infants and children; while preterm babies more often presented with bloody, mucoid stool and NEC, which is a picture different from that seen in elder infants and children.…”

Section: Discussionmentioning

confidence: 70%

“…Thus, we could not exclude the possibility of co-infection. Additionally, we did not survey the effect of breastfeeding on RV infection, which has been reported to be a protective factor for RV infection, 11,12,19 since this information was difficult to obtain from the medical records retrospectively.…”

Section: Discussionmentioning

confidence: 99%

Clinical manifestations of a cluster of rotavirus infection in young infants hospitalized in neonatal care units

Tai

Huang

Lien

et al. 2012

Journal of Microbiology, Immunology and Infection

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Clinical range of neonatal rotavirus gastroenteritis.

Cited by 55 publications

References 5 publications

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Emerging trends in acquired neonatal intestinal disease: is it time to abandon Bell's criteria?

Clinical manifestations of a cluster of rotavirus infection in young infants hospitalized in neonatal care units

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