Colorimetric detection of urine glucose using a C/CdTe QDs–GOx aerogel based on a microfluidic assay sensor

Hu, Tao; Xu, Kangkai; Qiu, Shanhu; Han, Yu; Chen, Juan; Xu, Jian; Chen, Ke; Sun, Zilin; Hong, Yuling; Zhang, Ni

doi:10.1039/d0tb00328j

Cited by 19 publications

(6 citation statements)

References 24 publications

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“…However, the underlying mechanism of the biological ligand effects of QD synthesis is unclear, which is a promising area for further exploration. Hu et al (2020b) used a C/CdTe QDs–GOx aerogel designed microfluidic assay glucose sensor based on colorimetric detection of urine glucose that the L-Cys-mediated synthesis of fluorescent CdTe QDs. The C/CdTe QDs–GOx exhibited a wide linear range of 0–13 mM and a low detection limit of 0.223 mM.…”

Section: Materials For Nanofiber-based Glucose Sensorsmentioning

confidence: 99%

Electrospun nanofiber-based glucose sensors for glucose detection

Zhang

Liu

et al. 2022

Front. Chem.

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Diabetes is a chronic, systemic metabolic disease that leads to multiple complications, even death. Meanwhile, the number of people with diabetes worldwide is increasing year by year. Sensors play an important role in the development of biomedical devices. The development of efficient, stable, and inexpensive glucose sensors for the continuous monitoring of blood glucose levels has received widespread attention because they can provide reliable data for diabetes prevention and diagnosis. Electrospun nanofibers are new kinds of functional nanocomposites that show incredible capabilities for high-level biosensing. This article reviews glucose sensors based on electrospun nanofibers. The principles of the glucose sensor, the types of glucose measurement, and the glucose detection methods are briefly discussed. The principle of electrospinning and its applications and advantages in glucose sensors are then introduced. This article provides a comprehensive summary of the applications and advantages of polymers and nanomaterials in electrospun nanofiber-based glucose sensors. The relevant applications and comparisons of enzymatic and non-enzymatic nanofiber-based glucose sensors are discussed in detail. The main advantages and disadvantages of glucose sensors based on electrospun nanofibers are evaluated, and some solutions are proposed. Finally, potential commercial development and improved methods for glucose sensors based on electrospinning nanofibers are discussed.

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Section: Materials For Nanofiber-based Glucose Sensorsmentioning

confidence: 99%

Electrospun nanofiber-based glucose sensors for glucose detection

Zhang

Liu

et al. 2022

Front. Chem.

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“…Furthermore, Hu et al 76 had produced a 3D aerogel microfluidic system to detect urinal glucose by using a fluorescent probe composed of green-fluorescent CDs (GCDs), red fluorescent cadmium telluride quantum dots (CdTeQDs) and glucose oxidase (GOx). As shown in Fig.…”

Section: Biosensingmentioning

confidence: 99%

Carbon dots and miniaturizing fabrication of portable carbon dot-based devices for bioimaging, biosensing, heavy metal detection and drug delivery applications

et al. 2022

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“…[26] Metal Organic Frameworks. [27,28] Nevertheless, the research focusing on developing an effective glucose sensor in varying dimensions is still progressing and highly motivated. In 2013, Xia and coworkers have developed a glucose oxidase functionalized fluorescent gold nanoclusters capped with tertrakis (hydroxyl methyl) phosphonium probe where thioctic acid modified glucose oxidase act as the precursor with a detection limit of 0.7×10 À 6 M. [19] Hence, Glucose oxidase (GOD) has focused on biological research and piqued the interest in numerous biological fields as well as in commercial applications.…”

Section: Introductionmentioning

confidence: 99%

“…Carbon dots [26] . Metal Organic Frameworks [27,28] . Nevertheless, the research focusing on developing an effective glucose sensor in varying dimensions is still progressing and highly motivated.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Enzymatic Sensor Based Glucose Oxidase Modified Bovine Serum Albumin‐Gold Nanoclusters for Detection of Glucose

Abraham,

Madanan,

Varghese

et al. 2024

ChemPlusChem

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An enzymatic fluorescent probe is developed for the selective detection of glucose. In this work, a Bovine Serum Albumin stabilized gold nanocluster (BSA‐AuNCs) was synthesized by microwave assisted method, and it is modified with glucose oxidase, thereby a fluorescent enzymatic sensor (BSA‐AuNCs@GoX) was designed for the sensitive detection of glucose with a limit of detection of 0.03 mM. The red fluorescence exhibited by the probe is quenched by the production of H2O2 on addition of glucose via. a static quenching mechanism from UV visible absorption and Fluorescence lifetime results. The developed probe exhibits good selectivity and sensitivity with other coexisting molecular species such as glycine, creatinine, methionine, histidine, uric acid, albumin, and ions such as sodium, potassium, calcium, magnesium, zinc etc. that appear in the body fluid. The practical applicability was studied in paper strip and extended its reproducibility in biological matrixes such as human serum and urine and found a good recovery percentage of 94‐101%. By this way, we have fabricated an effective fluorescent enzymatic “turn‐off” sensing probe for the detection of glucose.

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Colorimetric detection of urine glucose using a C/CdTe QDs–GOx aerogel based on a microfluidic assay sensor

Abstract: A sensitive fluorescent microfluidic sensor based on carbon quantum dots (CQDs), cadmium telluride quantum dots (CdTe QDs) aerogel and glucose oxidase (GOx) for urinal glucose detection was fabricated via a simple method.

Cited by 19 publications

References 24 publications

Electrospun nanofiber-based glucose sensors for glucose detection

Electrospun nanofiber-based glucose sensors for glucose detection

Carbon dots and miniaturizing fabrication of portable carbon dot-based devices for bioimaging, biosensing, heavy metal detection and drug delivery applications

Fluorescent Enzymatic Sensor Based Glucose Oxidase Modified Bovine Serum Albumin‐Gold Nanoclusters for Detection of Glucose

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