Comparison of oral and intravenous fluid therapy in newborns with hypernatremic dehydration

Erdemir, Aydın; Kahramaner, Zelal; Cosar, Hese; Türkoğlu, Ebru; Kanık, Ali; Sütçüoğlu, Sümer; Özer, Esra Arun

doi:10.3109/14767058.2013.819334

Cited by 13 publications

(14 citation statements)

References 15 publications

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“…There were no systematic reviews focusing on specifics of treatment and its outcomes and no randomized clinical trials. There were 7 retrospective [10,[21][22][23][24][25] and 2 prospective studies [26,27] with ≥ 5 patients included. Only 2 articles performed direct comparisons regarding different treatments [10,22] ( Table 1 ), while the remaining studies described types of treatment and outcomes and were kept in the review for descriptive purposes only ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…There were 7 retrospective [10,[21][22][23][24][25] and 2 prospective studies [26,27] with ≥ 5 patients included. Only 2 articles performed direct comparisons regarding different treatments [10,22] ( Table 1 ), while the remaining studies described types of treatment and outcomes and were kept in the review for descriptive purposes only ( Table 2 ). One article was a case series of neonates with severe hypernatremia treated with peritoneal dialysis (PD), and we decided to keep it in the review due to its data regarding outcomes of this specific therapy [25] .…”

Section: Resultsmentioning

confidence: 99%

“…One article was a case series of neonates with severe hypernatremia treated with peritoneal dialysis (PD), and we decided to keep it in the review due to its data regarding outcomes of this specific therapy [25] . Three articles included late preterm infants [22,26,28] and we also decided to keep it in the review as these sample included otherwise healthy neonates whose only likely predisposing factor related to hypernatremic dehydration was inadequate breastfeeding. These infants had a birth weight >2,000 g and were not admitted for other issues related to prematurity.…”

Section: Resultsmentioning

confidence: 99%

“…fluid group) developed seizures and cerebral edema. He had a 12mEq/L drop in SNa at 12 h. No further adverse effects of treatment were described and there was no follow-up for neurodevelopmental evaluation [22] .…”

Section: Resultsmentioning

confidence: 99%

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Treatment of Hypernatremia in Breastfeeding Neonates: A Systematic Review

Bischoff

Dornelles²,

Carvalho

2017

Biomed Hub

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Background/Aims: Hypernatremic dehydration in term neonates is associated with inadequate fluid intake, usually related to insufficient lactation. The use of hypotonic fluids is appropriate to dilute serum sodium (SNa), but cerebral edema may develop when it happens abruptly. Our objective was to clarify how to correct hypernatremic dehydration properly. Methods: The following databases were searched, limited to studies published until January What Is It about?Hypernatremic dehydration in term neonates is classically associated with inadequate fluid intake, particularly in breastfed infants. Although the literature proposes a maximum rate of serum sodium (SNa) reduction, there is no consensus about proper rehydration strategies in hypernatremic neonates. Both the degree of hypernatremia and the rate of SNa drop during treatment are key players in the development of serious adverse effects. We highlight the importance of conducting well-designed studies in order to elucidate remaining questions. case series evaluating relevant outcomes. Information regarding the way of administering the treatment, type of fluid used, rates of complications and outcomes, as well as the rate of SNa reduction were collected. Results: Searches yielded 771 articles: 64 had the full text reviewed and 9 were included. No randomized clinical trials or systematic reviews focusing on treatment of hypernatremic dehydration and its outcomes were found. We found a scarcity of high quality studies and great methodology heterogeneity. Conclusions: More severe hypernatremia is at greater risk of causing severe adverse effects of treatment. There is no consensus about the optimal rate of SNa drop in this population, but a slower correction appears to be safer. Questions as when parenteral fluids are indicated remain unanswered.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Treatment of Hypernatremia in Breastfeeding Neonates: A Systematic Review

Bischoff

Dornelles²,

Carvalho

2017

Biomed Hub

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“…In our study, the defining characteristic of sudden weight loss achieved a weighted score of 0.67. A study by Erdemir et al (2014) presents clinical characteristics accompanying hypernatraemic dehydration in newborns including: fever, hepatitis, weak suction, and restlessness. Similarly, Trotman et al (2004) and Uras et al (2007) report fever, weak suction, irritability, lethargy, sleepiness, hepatitis, vomiting, and low urine output.…”

Section: Sd -Standard Deviation; Ws -Weighted Score; Nanda -North Amementioning

confidence: 99%

Content Validation of Nursing Diagnosis of Deficient Fluid Volume [Dehydration] in the Context of Neonatological Nursing

Rabasová¹

2017

Cent Eur J Nurs Midw

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Aim: The aim of the study consisted in content validation of the defining characteristics, and related factors of the nursing diagnosis of Deficient fluid volume [Dehydration] (00027), from the perspective of neonatal nurses. Design: Content validation study. Methods: The defining characteristics of the nursing diagnosis of Deficient fluid volume [Dehydration] (00027) were evaluated with the help of the Fehring Diagnostic Content Validity Model. The set consisted of 125 experts/nurses. The significance of the defining characteristics was rated by the nurses on a Likert scale from 1 to 5. Data collection was carried out from March to September 2016. Results: seven characteristics from 32 were designated primary defining characteristics by the experts: decreased urine output, sunken fontanelle, change in skin turgor, dry mucous membranes, increased urine concentration, elevated haematocrit, and general appearance of exhaustion. 25 characteristics were designated secondary defining characteristics; 12 of which were characteristics from NANDA-I. Items such as: constipation, decreased pulse volume, cramps, absence of tears, and abdominal distension achieved a weighted score under 0.50. All from the group of related factors were defined as secondary by the experts. Conclusion: The set of experts regarded the primary significant characteristics for the determination of the nursing diagnosis of Deficient fluid volume [Dehydration] in newborns to consist in seven defining characteristics. All related factors were regarded to be secondary.

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