Comparison of transcatheter arterial chemoembolization combined with radiofrequency ablation or microwave ablation for the treatment of unresectable hepatocellular carcinoma: a systemic review and meta-analysis

Abstract

Background: Transcatheter arterial chemoembolization (TACE), radiofrequency ablation (RFA), and microwave ablation (MWA) are regarded as effective therapies for treating unresectable hepatocellular carcinoma (HCC). We conducted this study to compare the efficiency and safety of TACE combined with RFA (TR group) or MWA (TM group).

Chemoembolization Plus Microwave Ablation vs Chemoembolization Alone in Unresectable Hepatocellular Carcinoma Beyond the Milan Criteria: A Propensity Scoring Matching Study

“…25 MWA can effectively destroy some hypovascular HCC tumors that do not respond well to TACE treatment alone. [26][27][28][29] Another important finding of the study was that TACE following MWA may improve the downstaging rate significantly more than TACE alone. Liver transplantation is considered the standard therapy for HCC patients within MC, with a low recurrence rate (10%) and high 5-year survival rates (70%).…”

Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta‐analysis

“…The need of minimal invasion has already become a crucial consideration for therapeutic decision‐making in the SAUCCC 8–14 . Accordingly, HA and HATACE possess unique superiorities among multifarious therapies for appropriate HCC patients in the SAUCCC, 17–20,22–33,85–88 which is fully exhibited in the Data .…”

“…[8][9][10][11][12][13][14]26 The need of minimal invasion has already become a crucial consideration for therapeutic decision-making in the SAUCCC. [8][9][10][11][12][13][14] Accordingly, HA and HATACE possess unique superiorities among multifarious therapies for appropriate HCC patients in the SAUCCC, [17][18][19][20][22][23][24][25][26][27][28][29][30][31][32][33][85][86][87][88] which is fully exhibited in the Data S1. COVID-19 throughout the world has caused unprecedented social turmoil on a global level, triggering F I G U R E 3 Risk of bias summary before correction: each risk of bias item for each RCT of sensitivity analysis.…”

Transcatheter arterial chemoembolization followed by surgical resection for hepatocellular carcinoma: a focus on its controversies and screening of patients most likely to benefit

“…TACE is an attractive option because it can be administered regardless of the size, location, and the number of tumors [6] . With the recent advances in interventional radiology, TACE is now widely used as a palliative treatment for unresectable HCC [7–11] . TACE has also become one of the most widely used postoperative adjuvant treatments after SR [12–15] .…”