Complete atrioventricular canal repair with a decellularized porcine small intestinal submucosa patch

Haddad, Eliana Al; LaPar, Damien J.; Dayton, Jeffrey D.; Bacha, Emile A.

doi:10.1111/chd.12666

Cited by 4 publications

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A SIS-dECM patch, used to close ventricular and atrial septal defects in 73 paediatric CHD patients (average age 22 weeks) [117], showed lower rates of reoperations compared to other patch materials. Additionally, it exhibited more flexibility and ease of use.…”

Section: Xenografts For Chdmentioning

confidence: 91%

Biological Scaffolds for Congenital Heart Disease

et al. 2023

View full text Add to dashboard Cite

Congenital heart disease (CHD) is the most predominant birth defect and can require several invasive surgeries throughout childhood. The absence of materials with growth and remodelling potential is a limitation of currently used prosthetics in cardiovascular surgery, as well as their susceptibility to calcification. The field of tissue engineering has emerged as a regenerative medicine approach aiming to develop durable scaffolds possessing the ability to grow and remodel upon implantation into the defective hearts of babies and children with CHD. Though tissue engineering has produced several synthetic scaffolds, most of them failed to be successfully translated in this life-endangering clinical scenario, and currently, biological scaffolds are the most extensively used. This review aims to thoroughly summarise the existing biological scaffolds for the treatment of paediatric CHD, categorised as homografts and xenografts, and present the preclinical and clinical studies. Fixation as well as techniques of decellularisation will be reported, highlighting the importance of these approaches for the successful implantation of biological scaffolds that avoid prosthetic rejection. Additionally, cardiac scaffolds for paediatric CHD can be implanted as acellular prostheses, or recellularised before implantation, and cellularisation techniques will be extensively discussed.

show abstract

Section: Xenografts For Chdmentioning

confidence: 91%

Biological Scaffolds for Congenital Heart Disease

et al. 2023

View full text Add to dashboard Cite

show abstract

Different Forms of Decellularized Tissues and Their Characteristics, Applications in Tissue Repair as Well as Performance Optimization

Lei

Song

et al. 2021

Decellularized Materials

View full text Add to dashboard Cite

A surgical approach of an unusual variant of complete atrioventricular defect; A case report

et al. 2021

View full text Add to dashboard Cite

Background Complete atrioventricular canal is a congenital heart defect that is characterized by an atrial septal defect, ventricular septal defect, and a common atrioventricular valve. Standard surgical techniques for repairing complete atrioventricular canal defect mainly includes repairing the defect with a single patch, a double patch, or with the modified single patch technique. Case presentation This paper presents a novel surgical repair technique of an unusual anatomical presentation for a complete atrioventricular canal defect in a patient with Down syndrome. Conclusions Unusual anatomical variant for congenital heart defects occurs frequently, which gives surgeons real opportunities to innovate surgical approaches. This patient was an example of an unusual anatomical presentation for complete atrioventricular canal, and the surgical technique used for this patient was novel. Follow up for these patients is mandatory for long term results.

show abstract

Complete atrioventricular canal repair with a decellularized porcine small intestinal submucosa patch

Cited by 4 publications

References 29 publications

Biological Scaffolds for Congenital Heart Disease

Biological Scaffolds for Congenital Heart Disease

Different Forms of Decellularized Tissues and Their Characteristics, Applications in Tissue Repair as Well as Performance Optimization

A surgical approach of an unusual variant of complete atrioventricular defect; A case report

Contact Info

Product

Resources

About