Contribution of text Rasapaddhati in the history of Indian alchemy: A review

Khan³

et al. 2020

ijrps

COVID- 19 has created a lot of hazardous health issues worldwide. Research fraternity around the world is trying to find out vaccine or medicines against the virus. In this pandemic situation, there is a need for remedies to boost the immunity to fight against the virus. Ayurveda treatises have described several herbal drugs which are used as home remedies and are said to be effective against all microorganisms and effective in boosting immunity. Home remedies can be played a vital role as immunomodulant. Hence in this paper, an attempt is made to review such home remedies and identify its efficacy on various conditions. The relevant references were searched on the internet to find out the scientific data available on home remedies. Fumigation, Rasayan drugs, a decoction of herbal medicines found more useful. Tinospra cordifolia, Glycyrrhiza glabra, Ocimum sanctum, Withania somnifera, Curcuma longa are most decorated single herbal drugs used as home remedies for boosting the immunity. Considering the global disease burden caused by COVID-19, there is an urgent need to explore and widened the use of home remedies to fight against COVID-19 menace effectively.

Section: Introductionmentioning

confidence: 99%

COVID-19 Pandemic: Home Remedies for Immunity Boosting

Bhokardankar

Khan³

et al. 2020

ijrps

“…Herbo-mineral formulations hold a significant place in Ayurvedic pharmaceutics. Nearly 70 % of formulations include a combination of one or more metallic/mineral with several herbs which have a supporting role in improving efficacy, relieving symptoms of the disease and to achieve long and healthy life [1][2]. Rasaushadhies (metal and mineral) preparations are unique preparations that include Bhasma, herbomineral preparations and Kupipakwa rasayana.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Repeated Dose (Sub Chronic) Toxicity Study of Shilasindur Prepared by Two Different Methods Along with Its Characterization and Antimicrobial Activity

Tirpude

et al. 2022

JPRI

Self Cite

Introduction: Rasaushadhies (metal and mineral) preparations are unique preparations that include Bhasma, herbo-mineral preparations and Kupipakwa rasayana hold a significant place in Ayurvedic pharmaceutics. Nearly 70 % of formulations include a combination of one or more metallic/mineral with several herbs which have a supporting role in improving efficacy, relieving symptoms of the disease and to achieve long and healthy life. Shilasindur is a one of the Kupipakwa rasayana containing mercury, sulphur and arsenic disulphide and indicated in skin disorders, respiratory tract disorders and other infectious diseases. Aim and Objectives: Evaluation of repeated dose (Sub chronic) toxicity study of Shilasindur along with its characterization and antimicrobial activity. Materials & Methods: Shilasindur will be prepared in three batches as per classical reference and by using Electric Muffle furnace. The prepared formulation will be assessed with Organoleptic characters, physicochemical parameters and ICP – AES (Inductively coupled plasma atomic emission spectroscopy), FTIR (Fourier-transform infrared spectroscopy), XRD (X-Ray Diffraction). Sub chronic toxicity study will be carried out according to the OECD guidelines 408 and 452 as well as CCRAS guidelines of safety and toxicity. Epsilometer test (E-test) will be used to check antimicrobial activity of Shilasindur. Results: The analytical parameters will be assessed to establish the pharmaceutical standardization. Toxicity study will be done in three doses to ensure its safety. Statistical analysis will be done by applying unpaired t-test and ANOVA test. Conclusion: If significant positive results obtained in this work then it will be a valuable contribution and evidence that the drug Shilasindur is safe for consumption at treatment doses.

“…Rasashastra & Bhaishajya Kalpana is one among the branches of Ayurveda, which deals with Ayurvedic pharmaceutics. Rasashastra deals with pharmaceutical preparation of Ayurveda related to metallic origin [1]. Most emphasis is given with respect to the therapeutic uses of mercurial, mineral and metallic medicines including calcium containing formulations specified for various disease conditions [2].…”

Section: Introductionmentioning

confidence: 99%

Pharmaceutico-Analytical Study of Muktashukti Pishti and Muktashukti bhasma and Comparative Evaluation of their Relative Oral Bioavailability

Kamble

Wanjari

et al. 2021

JPRI

Self Cite

Background: Shukti (Oyster) is a very commonly occurring calcium form. It is rich source of calcium & minerals. As per text it can be converted into two forms which are bhasma (calcinated ash) and pishti (powdered form without agni).These forms may have different rate of absorption. This needs to be studied. Aim: To study Pharmaceutico-analytical study of Muktashukti pishti & Muktashukti bhasma and comparative evaluation of their relative oral bioavailability. Materials and methods: The two formulations will be prepared from shukti (oyster). By triturating with Gulabjala Muktashukti pishti will be prepared and by traditional puta method Muktashukti bhasma will be prepared. The prepared formulations will be assessed for Bhasma Pariksha mentioned in Ayurveda. Organoleptic characters, physicochemical parameters and Particle size distribution analysis, SEM-EDX (Scanning Electron Microscopy, Energy Dispersive X-Ray Analysis), FTIR (Fourier-transform infrared spectroscopy), XRD (X-Ray Diffraction), GCMS (Gas Chromatography Mass Spectrometry) will be evaluated. To assess the relative oral bioavailability of Muktashukti pishti & Muktashukti bhasma study will be conducted in healthy volunteers and will be compared with the standard calcium supplement. The study will be conducted in between two test groups and standard group. Observation and results: The analytical parameters will be assessed and compared in Muktashukti bhasma and Muktashukti pishti. For relative oral bioavailability Blood serum calcium will be assessed in all three groups. By applying unpaired “t” Test, One-way ANOVA the statistical significance can be measured. Conclusion: The pharmaceutical & analytical study of Muktashukti pishti and Muktashukti bhasma will provide the standard parameters and clinical comparative evaluation with standard will generate evidence for better bioavailability.