Background: Shukti (Oyster) is a very commonly occurring calcium form. It is rich source of calcium & minerals. As per text it can be converted into two forms which are bhasma (calcinated ash) and pishti (powdered form without agni).These forms may have different rate of absorption. This needs to be studied.
Aim: To study Pharmaceutico-analytical study of Muktashukti pishti & Muktashukti bhasma and comparative evaluation of their relative oral bioavailability.
Materials and methods: The two formulations will be prepared from shukti (oyster). By triturating with Gulabjala Muktashukti pishti will be prepared and by traditional puta method Muktashukti bhasma will be prepared. The prepared formulations will be assessed for Bhasma Pariksha mentioned in Ayurveda. Organoleptic characters, physicochemical parameters and Particle size distribution analysis, SEM-EDX (Scanning Electron Microscopy, Energy Dispersive X-Ray Analysis), FTIR (Fourier-transform infrared spectroscopy), XRD (X-Ray Diffraction), GCMS (Gas Chromatography Mass Spectrometry) will be evaluated. To assess the relative oral bioavailability of Muktashukti pishti & Muktashukti bhasma study will be conducted in healthy volunteers and will be compared with the standard calcium supplement. The study will be conducted in between two test groups and standard group.
Observation and results: The analytical parameters will be assessed and compared in Muktashukti bhasma and Muktashukti pishti. For relative oral bioavailability Blood serum calcium will be assessed in all three groups. By applying unpaired “t” Test, One-way ANOVA the statistical significance can be measured.
Conclusion: The pharmaceutical & analytical study of Muktashukti pishti and Muktashukti bhasma will provide the standard parameters and clinical comparative evaluation with standard will generate evidence for better bioavailability.
Purpose:Aacharya Charaka has mentioned the Aachara rasayana for perfect mental, physical, social, spiritual health of human being. Aachar means behavioural discipline which guides and motivates the persons to have social happiness and mental stability. In this competitive era with hectic schedules, it s the need of hour to follow Achar rasayan for leading healthy, mentally peaceful life. Today's youth are deviating themselves by improper or unethical conduct. The purpose of this study is to reveal whether the students of ayurveda, who are aware of achar rasayan are practising it & upto what extent; & secondly to establish an interrelation of achar rasayan on their physical mental health & effect on academic performance as well as social behaviour.Method:66 students of final BAMS of Mahatma Gandhi Ayurved college, Wardha were selected for the survey by an objective questionnaire by single blind method. On the basis of answered questionnaire, the students were categorized into three groups viz; poorly following, moderately following & strongly following Achar rasayan. Also students were assessed on various observations like health status, Academic performance, Attendance, participation in co curricular & extra curricular activities, Behaviour with teachers & peers.Result:Out of 66 students, 17 who strongly followed Achar rasayan, were good at academics, enjoying good physical & mental health & friendly reputation among peers. Moderately following 36 students. had variability of students enjoying satisfactory to good physical & mental health, minor health problems, intermittent stress & few didn’t have healthy peer relation. 13 students poorly followed Acharrasayan were comparatively slow learners & significant low attendance was found in 7 students due to various reasons.Conclusion:The study concludes that following Achar rasayan leads to a good physical, mental & social health.
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