2014
DOI: 10.1107/s1600536814018042
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Crystal structure of 4-allylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine

Abstract: In the title compound, C8H8N4S, the pyrazolo­[3,4-d]pyrimidine ring system is essentially planar, with a maximum deviation from the mean plane of 0.025 (3) Å. The allyl group is disordered over two sites in a 0.512 (6):0.488 (6) ratio. In the crystal, mol­ecules are linked by pairs of N—H⋯N hydrogen bonds, forming inversion dimers with an R 2 2(8) graph-set motif.

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Cited by 5 publications
(3 citation statements)
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“…antagonists (Taliani et al, 2010 and as antitubercular agents (Trivedi et al, 2012 (El Fal et al, 2014;El Fal et al, 2015;Ahoya et al, 2011, Anothane et al, 2012.…”
Section: Related Literaturementioning
confidence: 99%
“…antagonists (Taliani et al, 2010 and as antitubercular agents (Trivedi et al, 2012 (El Fal et al, 2014;El Fal et al, 2015;Ahoya et al, 2011, Anothane et al, 2012.…”
Section: Related Literaturementioning
confidence: 99%
“…(Chauhan et al, 2013), antitubercular (Venkatesan et al, 2014) and anticancer (Rashad et al, 2011) agents. During the search for new antibacterial agents synthesis, some 1H-pyrazolo [3,4-d] pyrimidine-4-thiol derivatives were prepared (El Fal et al, 2013, 2014a, 2014bOuzidan et al, 2011). These compounds are currently under investigation for possible biological activity.…”
Section: Related Literaturementioning
confidence: 99%
“…In continuation of our work on the synthesis of the excess of allopurinol [16][17][18][19][20][21][22][23], we have envisioned the synthesis new pyrazolo [3,4-b]pyridine derivatives by thionation, alkylation and 1,3-dipolar cycloaddition reactions in order to evaluate their inhibitory effect of α-amylase and α-glucosidase. The melting points were taken on an electrothermal capillary melting point apparatus.…”
Section: Introductionmentioning
confidence: 99%