The following article is part of a series in an initiative by the American Head and Neck Society's Education Committee and will review clinical practice guidelines for head and neck oncology. The primary goal is to increase awareness of current best practices pertaining to head and neck surgery and oncology. This manuscript is a review of current knowledge in laryngeal cancer with a focus on anatomy, epidemiology, diagnosis, evaluation, and treatment.
K E Y W O R D Shead and neck cancer, laryngeal cancer
| I NT ROD UCTI ONThe larynx is critical in the function of swallow, speech, and respiration. The larynx is a structure responsible for maintaining and protecting the airway, vocalization, and protecting the lungs from inhaled gases, liquids, and solids. Elevation of the larynx aids in swallowing function, and the ability to generate pressure with glottis closure is important for straining and gastrointestinal function. Malignancies that affect the larynx have an impact on all of the physiologic functions of the larynx in varying degrees. Laryngeal cancer is the second most common head and neck cancer worldwide. This article provides an overview of our current knowledge on laryngeal cancer, including anatomy, epidemiology, diagnosis, evaluation, and treatment.