Cutaneous Malignant Melanoma in Rochester, Minnesota: Trends in Incidence and Survivorship, 1950 Through 1985

Popescu, N; Beard, C. Mary; Treacy, Patrick-Julien; Winkelmann, R. K.; O’Brien, Peter C.; Kurland, Leonard T.

doi:10.1016/s0025-6196(12)62140-5

Cited by 33 publications

(23 citation statements)

References 19 publications

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“…This improvement is likely to reflect an increased diagnostic awareness toward cutaneous pigmented lesions, partly following organized information campaigns (Bulliard et al, 1992;Herd et al, 1995). 1980-1984 1985-1989 1990-1994 1980-1984 1985-1989 1990-1994 Canton of Vaud, Switzerland, 1980 The major interest and importance of this work is related to the multivariate approach in the survival analysis, which was able to simultaneously consider patients' and tumors' characteristics in the same proportional hazard model, and hence to identify and quantify the independent role of each of these factors on long-term prognosis of cutaneous malignant melanoma (Lee, 1996;Popescu et al, 1990). Most previous work, in fact, tended to consider only a few prognostic factors separately (Mänsson-Brahme et al, 1994;Nelemans et al, 1993), although multivariate analyses and interactions were considered in some of these (Cox et al, 1996;Helfenstein et al, 1996).…”

Section: Discussionmentioning

confidence: 99%

Prognostic factors for cutaneous malignant melanoma in Vaud, Switzerland

et al. 1998

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Section: Discussionmentioning

confidence: 99%

Prognostic factors for cutaneous malignant melanoma in Vaud, Switzerland

et al. 1998

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“…Among Caucasian populations, melanoma is more frequently reported on the backs and shoulders of men and the lower limbs of women (76)(77)(78)(79)(80). For both sexes, given that these body site locations are associated with lower sunlight exposure, these findings have been used as supportive evidence for the intermittent UV exposure theory (81,82).…”

Section: Anatomic Distributionmentioning

confidence: 95%

Epidemiology of Melanoma

Matthews

Qureshi

et al. 2017

Cutaneous Melanoma: Etiology and Therapy

275

321

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Melanoma is a potentially lethal cancer that is most commonly cutaneous. The worldwide incidence of melanoma has risen rapidly over the course of the last 50 years. Its incidence is greatest among fair-skinned populations, and in regions of lower latitude. Incidence is greater among geriatric populations, but melanoma is also among the most common cancers found in adolescent and young adult populations. In fact, it is one of the leading cancers in average years of life lost per death from disease. Melanoma incidence varies by sex, which is also associated with differences in melanoma anatomic site. Similar differences by region, ethnicity, age, and sex are observed in mortality rates of melanoma. In the setting of rising incidence and mortality, melanoma bears a heavy health and economic burden. Attributable costs are several billion in nations with greater melanoma incidence. Preventative strategies have been implemented in multiple high-risk regions with variable success. It is imperative that research efforts Epidemiology of Melanoma 4 achieve better understanding of the risk factors and etiology of disease, with the goal to halt and reverse the progressive trend of rising incidence and mortality from melanoma.

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“…Identified by the government's Health of the Nation Strategy on account of its rising incidence and apparently high potential for prevention (Anonymous, 1992;Anonymous 1993), additional concern has resulted from the anticipated health effects of the thinning of the ozone layer. The target of this strategy is to halt the year-on-year increase in incidence of skin cancer by the year 2005, There is strong evidence, based upon mortality and cancer registration data that malignant melanoma (MM) has become more common in many countries over the last 30 years (Streetly and Markowe, 1995;MacKie et al, 1985;Popescu et al, 1990;Bonett et al, 1989;Elder, 1995). However, trends in non-melanoma skin cancer (NMSC) are less certain, largely because many cancer registers do not include these tumours, and for those that do underascertainment is a significant problem (Beadle et al, 1982).…”

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confidence: 99%

Non-melanoma skin cancer and solar keratoses. I. Methods and descriptive results of the South Wales Skin Cancer Study

Harvey

Frankel²,

Marks³

et al. 1996

Br J Cancer

115

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Summary This study aimed to describe the prevalence and incidence of solar keratoses and skin cancers and the natural history of solar keratoses in a random population sample. It was a cross-sectional study, with follow-up, conducted in South Wales, and involved 1034 subjects aged 60 years and over drawn from the Family Health Services Authority register. The main outcome measures were detection of the presence of solar keratoses and skin cancers on sun-exposed skin and photographic validation of solar keratoses and biopsy confirmation of cancers wherever possible. We found that solar keratosis prevalence was 23% (95% confidence interval 19.5-26.5) and that of skin cancer (all types) 2% (95% confidence interval 1.0-3.5). The incidence rate of solar keratoses was 149 lesions per 1000 person-years and of non-melanoma skin cancer 9 per 1000 person-years. In all 21% (95% CL 16-26) of solar keratoses regressed spontaneously during follow-up. None underwent malignant change. We believe that the failure of individuals to seek medical advice and the variable under-registration of non-melanoma skin cancer makes population-based study important. The high prevalence and incidence of malignant and pre-malignant skin lesions in this random sample raise major public health concerns. The high rate of spontaneous regression of solar keratoses and the low rate of malignant change challenges conventional views about the need for routine treatment of these lesions.

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Cutaneous Malignant Melanoma in Rochester, Minnesota: Trends in Incidence and Survivorship, 1950 Through 1985

Cited by 33 publications

References 19 publications

Prognostic factors for cutaneous malignant melanoma in Vaud, Switzerland

Prognostic factors for cutaneous malignant melanoma in Vaud, Switzerland

Epidemiology of Melanoma

Non-melanoma skin cancer and solar keratoses. I. Methods and descriptive results of the South Wales Skin Cancer Study

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