Cytolo-histological correlation of breast lump-as a part of internal quality control

K, Shanmugasamy; K, Anandraj Vaithy; Bhavani, K; Kotasthane, Dhananjay Shrikant

doi:10.5958/2394-6792.2016.00062.4

Cited by 3 publications

(2 citation statements)

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“…The results of Dr manju et al [9] . ; Shanmugasamy K et al [10] were quite comparable to the findings of our studies. In the present study, False positive results were very minimal compared to False negative results.False negative and inconclusive reports were commonly resulted from hemorrhagic aspirates from highly vascular tumors , acellular aspirates from very hard lumps, and aspirates from cystic lumps and sampling error.…”

Section: Discussionsupporting

confidence: 92%

Study of Histopathological Correlation of Breast Mass with Radiological and Cytological Findings

Sarangan¹,

Geetha²,

Raj³

et al. 2017

IOSR JDMS

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Section: Discussionsupporting

confidence: 92%

Study of Histopathological Correlation of Breast Mass with Radiological and Cytological Findings

Sarangan¹,

Geetha²,

Raj³

et al. 2017

IOSR JDMS

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“…Studies done byPuja B. Jarwani et al 8 and Ambedkar Raj, KulandaiVelu et al 9 , showed that breast FNAC had a sensitivity ranging from 82% to 97.5% and specificity of more than 99%, which is comparable to our study. Study done by Shanmugasamy K et al 10 showed that the sensitivity, specificity and diagnostic accuracy of breast FNAC in diagnosis of malignancy was 93.5%,100%and 98.3% respectively. Zhang Qin et al in their study reported a sensitivity and specificity of 97.1% and 97.3% respectively for FNAC in diagnosing breast lesions.…”

Section: Discussionmentioning

confidence: 99%

Radiological and Cytological Correlation of Breast Lesions with Histopathological Findings in a Tertiary Care Hospital in Costal Karnataka

Richie¹,

Mellonie²

2019

IJCMR

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Introduction: Breast cancer is the leading cause of cancer deaths among women worldwide. Breast cancer clinically presents as breast lump.Fine needle aspiration cytology (FNAC) and breast ultrasound (sonomammography) is pivotal in characterization of a breast lump as benign and malignant lesion. There is a need to study radiological and cytological correlation of breast lesions with histopathological findings to evaluate the diagnostic accuracy of sonomammography and FNAC. Material and Methods: A prospective, quantitative and descriptive study was conducted in the department of Radiology, Father Muller Medical College Hospital, Mangalore. Patients who were evaluated for suspicious breast lump with a breast ultrasound, FNAC and biopsy from January 2017 to December 2018 were included in the study. Results: In this study, diagnostic accuracy for breast FNAC (98.7%) was found to be better than that of sonomammography (92.5%). Fine needle aspiration cytology of breast lump plays an important role when it is difficult to determine the nature of breast lump by clinical and radiological examination. In this study breast FNAC was found to have sensitivity of 98.4% and specificity of 95.7%. Sonomammography had a sensitivity of 90.6%and specificity of 97.8. Conclusion: Present study confirms the higher combined sensitivity, specificity and accuracy for ultrasonography and fine needle aspiration cytology in categorisation of breast lump as benign and malignant. USG is better indetection of benign lesions whereas cytology is better in case of malignancies. The triple assessment is an accurate, simple and cost-effective method for the evaluation of breast cancer and can be applied at our centre as a safe alternative for open biopsy when it is concordant and open biopsy must be reserved only for discordant results. This will subsequently reduce the number ofbreast biopsies significantly.

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Cytological Study of Breast Lesions with Histopathological Correlation

Gore

Shivaji

et al. 2021

Medical Journal of Dr. D.Y. Patil Vidyapeeth

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Introduction: Breast disease is the most common and ranks first among malignant tumors affecting females in many parts of the world. Timely and accurate diagnosis of a breast lump is lifesaving. Fine-needle aspiration cytology (FNAC) is a simple, safe, inexpensive method with wide acceptance and used as a first-line diagnostic procedure for diagnosis of breast lesions. Aim: The aim of the study was to diagnose any palpable lump of the breast in females by cytology and correlate with histopathology wherever possible. Setting and Design: This was a retrospective and prospective descriptive study carried out in the pathology department at our institute. Materials and Methods: This study was done for 2 years. FNAC of breast lesions was done, processed routinely, and stained with Papanicolaou stain. Histopathological correlation was done wherever possible on Tru-cut biopsies, excisional biopsies, and surgical specimens received. Statistical Analysis: The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated. Results: Among 304 cases, 229 were benign and 75 were malignant on cytology. Out of this, 79 cases underwent histopathological examination, in which 32 were benign and 47 were malignant cases. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the present study were 79.16%, 96.77%, 97.73%, 75%, and 86.08% respectively. Conclusion: The FNAC is an important preliminary diagnostic test in palpable breast lumps and the results show a high degree of correlation with a final histopathological report.

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Cytolo-histological correlation of breast lump-as a part of internal quality control

Cited by 3 publications

References 0 publications

Study of Histopathological Correlation of Breast Mass with Radiological and Cytological Findings

Study of Histopathological Correlation of Breast Mass with Radiological and Cytological Findings

Radiological and Cytological Correlation of Breast Lesions with Histopathological Findings in a Tertiary Care Hospital in Costal Karnataka

Cytological Study of Breast Lesions with Histopathological Correlation

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