DAYA HAMBAT KUNYIT (Curcuma longa linn) TERHADAP PERTUMBUHAN Candida albicans

Mubarak, Zaki; Gani, Basri A.; Mutia,

doi:10.24815/cdj.v11i1.13621

Cited by 3 publications

(5 citation statements)

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“…The inhibition zone is formed due to the process of absorption of antifungal substances (essential oils) into the agar media that has been planted with fungi (Nadifah et al, 2018). Mubarak, et al (2019) stated that turmeric extract can inhibit the growth of Candida albicans in various concentrations. The inhibition test in this study used the agar diffusion method (Kirby-Bauer) with 100 g nystatin as a positive control and blank disc paper as a negative control.…”

Section: Resultsmentioning

confidence: 99%

“…The diameter of the largest inhibition zone was seen at a concentration of 100% turmeric extract, which was 10.3 mm, and the smallest diameter was seen at a concentration of 12.5%, which was 6.6 mm. (Mubarak et al, 2019).…”

Section: Resultsmentioning

confidence: 99%

“…Curcumin, dimethoxy curcumin, and bisdementhoxy curcumin belong to the class of phenolic compounds as antifungals that can inhibit the growth of Candida albicans by damaging cell membranes and protein denaturation. (Mubarak et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

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Potential Inhibitory Power of "Curcuma Longa Linn." Extract Against Candida Albicans Fungus

Yuditha

Rafana

Kusparmanto

2022

MIRSHuS

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Oral candidiasis is a fungal infection that often appears on the oral mucosa. These lesions are caused by the fungus Candida albicans. Candida albicans is the most common pathogenic Candida species causing fungal infections of the oral cavity. The use of antifungal drugs is the most common way of giving, but there are many side effects that can be caused. Herbal ingredients that have antifungal effects can be alternative therapies with fewer side effects, one of which is turmeric (Curcuma longa Linn.). Turmeric has various compounds that have the potential as antifungals including curcumin, flavonoids, and essential oils that work by inhibiting the growth of fungi including Candida albicans. The purpose of this literature study is to provide scientific evidence related to the potential inhibition of turmeric extract (Curcuma longa Linn.) against Candida albicans. This writing is a literature study made based on reference sources or references obtained from journals accessed through the databases of Google Scholar, Hindawi, PubMed, Scopus, DOAJ, Research Gate and textbooks. The results of the study stated that turmeric extract had an inhibitory effect on the growth of Candida albicans, the greater the concentration of turmeric extract used, the greater the inhibition caused. Turmeric also has fewer side effects than antifungal drugs.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Potential Inhibitory Power of "Curcuma Longa Linn." Extract Against Candida Albicans Fungus

Yuditha

Rafana

Kusparmanto

2022

MIRSHuS

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“…Mekanisme kerja dari kurkurmin yaitu dengan cara merusak dinding sel danmendenaturasi protein sel, sehingga menjadi lisis. Hal ini diperkuat oleh pernyataan dari Mubarak et al (2019) menyatakan bahwa kurkumin merupakan senyawa fenolyang mempunyai sifat anti jamur. Sedangkan cara kerja flavonoid sebagai anti jamur yaitu menyerang membran sel dengan cara memecah lapisan dinding sel akibat perubahan komponen organik dan transportasi nutrisi yang disebabkan olehgugus hidroksil yang dimilikinya.…”

Section: F Perkembangan Embriounclassified

Pengaruh flavonoid dan kurkumin dalam ekstrak kunyit sebagai media perendaman terhadap daya tetas telur gurami (Osphronemus gouramy)

Mustofa

Nugroho

Subandiyono

2022

SAT

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Benih gurami yang masih mengandalkan dari alam serta pemijahan induk yang terjadi secara musiman merupakan kesulitan tersendiri, karena berakibat pada ketersediaan benih yang tidak kontinyu dan terbatas. Rendahnya nilai derajat penetasan telur merupakan suatu kendala dalam pembenihan gurami. Hal ini disebabkan karena telur gurami banyak ditumbuhi jamur pada saat proses penetasan, sehingga menyebabkan telur tidak menetas. Upaya yang dapat dilakukan untuk menghambat pertumbuhan jamur yaitu dengan perendaman larutan ekstrak kunyit pada proses penetasan telur. Ekstrak kunyit memiliki kandungan flavonoid dan kurkumin yang berperan dalam menghambat pertumbuhan jamur. Penelitian ini bertujuan untuk mengetahui pengaruh perendaman ekstrak kunyit pada telur gurami terhadap daya tetas telur gurami dan survival rate (SR) dari larva gurami. Selain itu, penelitian ini juga bertujuan untuk mengetahui ketahanan hidup larva gurami tanpa diberi pakan. Penelitian ini dilaksanakan di Balai Benih Ikan (BBI) Mungseng, Temanggung, pada bulan November 2020 hingga Februari 2021. Telur uji yang digunakan berasal dari Banjarnegara dan Magelang. Penelitian dilakukan dengan menggunakan metode ekseprimen rancangan acak lengkap (RAL) dengan 4 perlakukan dan 3 ulangan yakni A (0 ml/l), B (6 ml/l), C (8 ml/l) dan D (10 ml/l). Variabel yang diukur meliputi daya tetas (HR), kematian larva, perkembangan embrio, dan kualitas air. Hasil penelitian menunjukkan bahwa perendaman telur gurami kedalam ekstrak kunyit berpengaruh nyata (P<0,05) terhadap daya tetas (HR) telur gurami. Hasil penelitian menunjukkan bahwa hasil daya tetas (HR) telur gurami perlakuan D 96,67±2,89%, C 95,00±5,00%, B 91,67±5,7 dan A 83,33±2,89%. Kualitas air untuk suhu yaitu 28°C, DO berkisar antara 5,0-5,7 mg/l dan pH berkisar antara 6,5-7,1. Kata-kunci: Daya tetas, gurami, ketahanan hidup, kunyit, telur

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“…2 This disease could result in oral discomfort, dysphagia, taste sensation disorder, and malnutrition. 3 It can be caused by several factors, including systemic diseases such as diabetes mellitus, immunosuppressive condition, HIV, chemotherapy, malignancy such as leukemia, smoking habit, the use of dentures, xerostomia, and long-term medication such as antibiotics. 4 Prolonged use of antifungal drugs could cause several side effects such as a burning sensation due to irritation from nystatin and miconazole.…”

Section: Introductionmentioning

confidence: 99%

ANTIFUNGAL EFFECT OF MAULI BANANA STEM EXTRACT, BASIL LEAF EXTRACT, AND THEIR COMBINATION ON Candida albicans

Waskito¹,

Apriasari²,

Utami³

2020

Dentino

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Backgrounds: Oral candidiasis is an oral infection caused by abnormal growth of Candida albicans. The use of 0.2% chlorhexidine gluconate as a prophylactic mouthwash is conducted for oral candidiasis therapy. Prolonged use of 0.2% chlorhexidine gluconate is recorded to instigate side effects. Mauli banana stem extract and basil leaf extract demonstrate antifungal properties ascribed to their contents. Objective: To prove that the antifungal effect of 25% concentration of mauli banana stem extract, 12.5% concentration of basil leaf extract, and 25%, 50%, and 75% concentration of mauli banana stem and basil leaf combination extract on Candida albicans are comparable to 0.2% chlorhexidine gluconate. Methods: This study was resolved by applying the true experimental design with post-test only and control group design which consisted of 6 treatments. Group I was given Mauli banana stem extract with 25% concentration, group II was given basil leaf extract with 12.5% concentration, group III, IV, and IV were given the combination of Mauli banana stem and basil leaf extracts with 25%, 50%, and 75% concentrations, respectively. Meanwhile, group VI was given 1% chlorhexidine gluconate as a positive control. Each treatment was served with four times repetition. Antibacterial effectivity was assessed through the inhibition zone measurement of 0.2% chlorhexidine gluconate growth using the diffusion method. Results: This study revealed that the average diameter of inhibition zone formed in group I was 6-6.3 mm, group II was 6-6.2 mm, group III was 6-6.2 mm, group IV was 7-7.2 mm, group V was 10.2-11.4 mm, and group VI was 23.7-24.8 mm. Conclusion: The antifungal effect of mauli banana stem extract at 25% concentration, basil leaf extract at 12.5% concentration, and mauli banana stem and basil leaf combination extract at 25%, 50%, and 75% concentration on Candida albicans has been proven but not equivalent to 0.2% chlorhexidine gluconate.Keywords: Basil leaf extract, Candida albicans,inhibition zone, 0.2% chlorhexidine gluconate, diffusion method, Mauli banana stem extract,.

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DAYA HAMBAT KUNYIT (Curcuma longa linn) TERHADAP PERTUMBUHAN Candida albicans

Cited by 3 publications

References 1 publication

Potential Inhibitory Power of "Curcuma Longa Linn." Extract Against Candida Albicans Fungus

Potential Inhibitory Power of "Curcuma Longa Linn." Extract Against Candida Albicans Fungus

Pengaruh flavonoid dan kurkumin dalam ekstrak kunyit sebagai media perendaman terhadap daya tetas telur gurami (Osphronemus gouramy)

ANTIFUNGAL EFFECT OF MAULI BANANA STEM EXTRACT, BASIL LEAF EXTRACT, AND THEIR COMBINATION ON Candida albicans

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