2018
DOI: 10.22159/ajpcr.2018.v11i1.21982
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Design and Characterization of Oroslippery Buoyant Tablets for Ranitidine Hydrochloride

Abstract: Objective: The goal behind of performing this study was to come out with an oroslippery buoyant ranitidine hydrochloride tablet to ease the swallowing process. Hence, the drug is released controllably in the stomach regardless of the effect on gastric emptying time. Materials and Methods:The core of the buoyant containing 150 mg of the drug was compressed directly, and sodium bicarbonate was employed as an effervescent agent, besides, hydroxyl propyl methyl cellulose (HPMC) polymer was utilized in different gr… Show more

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Cited by 3 publications
(1 citation statement)
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“…However, Poly (Ethylene Glycol) Diacrylate (PEGDA) hydrogels were successfully printed, with a mechanical strength six times that of a conventional hydrogel. This indicates that the hydrogels that have been produced are robust enough to sustain their own weight, making them ideal for use as an implant and in situ [118].…”
Section: Nanocomposite Development For Medical Purposes Using 3d Prin...mentioning
confidence: 98%
“…However, Poly (Ethylene Glycol) Diacrylate (PEGDA) hydrogels were successfully printed, with a mechanical strength six times that of a conventional hydrogel. This indicates that the hydrogels that have been produced are robust enough to sustain their own weight, making them ideal for use as an implant and in situ [118].…”
Section: Nanocomposite Development For Medical Purposes Using 3d Prin...mentioning
confidence: 98%