Desmoplastic infantile ganglioglioma: CT and MRI features

Tenreiro-Picon, O. R.; Kamath, S. V.; Knorr, John R.; Ragland, Ronald L.; Smith, Thomas W.; Lau, K Y

doi:10.1007/bf02015789

Cited by 55 publications

(22 citation statements)

References 9 publications

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“…In infants, it is frequently associated with rapid head growth. The DIG has typical imaging features, which include (1) a large cystic and a small cortical solid component which is intensely enhanced by contrast medium, (2) location in the frontal and parietal lobes, with relative sparing of the occipital lobe, (3) apposition to a meningeal surface, and/or (4) contrast enhancement along the meningeal side of the mass [2, 3, 4, 5]. Total or nearly total surgical resection has been shown to result in a favorable outcome [6].…”

Section: Discussionmentioning

confidence: 99%

Chronological Changes on Magnetic Resonance Images in a Case of Desmoplastic Infantile Ganglioglioma

Tseng

Kuo

et al. 2002

Pediatr Neurosurg

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Desmoplastic infantile gangliogliomas (DIGs) are rare tumors during infancy. They often occur as huge cystic tumors in the frontal and parietal lobes, with their solid component being adjacent to the leptomeningeal membrane. This report presents a patient with DIG and intractable epilepsy. Due to hesitation by the patient’s family in allowing surgery, this is the first time that the chronological changes in DIG have been observed on imaging studies. During the follow-up, the tumor changed from a pure solid tumor to a cystic one, which is a typical picture of DIG. Surgical pathology confirmed the diagnosis of DIG. However, for a patient with epilepsy, it is recommended that this condition should be treated immediately with surgery.

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Section: Discussionmentioning

confidence: 99%

Chronological Changes on Magnetic Resonance Images in a Case of Desmoplastic Infantile Ganglioglioma

Tseng

Kuo

et al. 2002

Pediatr Neurosurg

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“…The mean MIB-1 labelling index in our cases was 1.5%. Other studies have shown Ki-67 labelling indices to range from 0.5% to 5% [20,22], confirming the benign nature of these neoplasms.…”

Section: Discussionmentioning

confidence: 52%

Desmoplastic infantile ganglioglioma ? clinicopathological and immunohistochemical study of four cases

Rout

Santosh

Mahadevan

et al. 2002

Child's Nervous System

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“…The frontal and parietal lobes are the most common sites, with lesions of the temporal and occipital lobes reported in smaller numbers. Extension of the enhancement to the leptomeningeal margin is characteristic on both CT and MR images and correlates with the firm dural attachment noted in many cases (Figs 7, 8) (47,50,51). It enhances intensely following intravenous administration of contrast media (47).…”

Section: Desmoplastic Infantile Gangliogliomamentioning

confidence: 62%

From the Archives of the AFIP

Koeller¹,

Henry²

2001

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Glial neoplasms that are peripherally located and involve the cortical gray matter are noteworthy because of their predilection to serve as a seizure locus, their amenability to surgical resection, their generally favorable prognosis, and their characteristic imaging features, which facilitate diagnosis before surgery. The smaller lesions include ganglioglioma and dysembryoplastic neuroepithelial tumor. Gangliogliomas contain both neuronal and glial components and occur most commonly in the temporal lobe. Variant forms of gangliogliomas may occur and are related to the different compositions of the underlying cellular population. Gangliocytomas lack glial cells and are located both in the cerebral hemispheres and the cerebellum. Lhermitte-Duclos disease represents a specific type of cerebellar gangliocytoma with dysplastic features and is characterized by a laminar pattern at imaging. Dysembryoplastic neuroepithelial tumors occur predominantly in children and young adults with partial seizures and most commonly arise in the temporal lobe, frequently in combination with cortical dysplasia. Surrounding vasogenic edema is conspicuously absent in both gangliogliomas and dysembryoplastic neuroepithelial tumors. The larger masses in this group include desmoplastic infantile ganglioglioma and pleomorphic xanthoastrocytoma and tend to involve the leptomeninges and cortical territory. Both invoke an intense desmoplastic reaction, which appears as an enhancing soft-tissue component at imaging.

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Desmoplastic infantile ganglioglioma: CT and MRI features

Cited by 55 publications

References 9 publications

Chronological Changes on Magnetic Resonance Images in a Case of Desmoplastic Infantile Ganglioglioma

Chronological Changes on Magnetic Resonance Images in a Case of Desmoplastic Infantile Ganglioglioma

Desmoplastic infantile ganglioglioma ? clinicopathological and immunohistochemical study of four cases

From the Archives of the AFIP

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