Detection and identification of potential transglutaminase 2 substrates in the mouse renal glomeruli

Cloning and expression of maize transglutaminase gene inEscherichia coliand its action over dairy proteins

“…The cross‐linking reactions induced by transglutaminase provide significant alterations in the protein molecules present in food matrices, leading to their better texture, stability, gelation, emulsifying potential, and water‐binding capacity, without any negative change in the sensory or nutritional quality (Gaspar, de Góes‐Favoni, & Pedroso., 2015; Ito, Tatsukawa, Yamaguchi, Takahashi, & Yuzawa, 2018). The strength of yogurt gel added with recombinant TGase was significantly higher than that of the control group.…”

Role of gut–kidney axis in renal diseases and IgA nephropathy

“…Moreover, when IgA1 deposits are cleared using an IgA1 protease, TG2 and TfR1 expression are no longer detectable [81]. TG2 is also expressed on other kidney cell types, such as tubular cells [82], which could also impact IgA-N progression. Moreover, TG2 concentration in urine from IgAN patients correlated with proteinuria and distinguished active and nonactive patients [83].…”