2017
DOI: 10.1016/j.microc.2016.09.002
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Determination of podophyllotoxin and related aryltetralin lignans by HPLC/DAD/MS from Lamiaceae species

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Cited by 18 publications
(13 citation statements)
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“…Wild Leptohyptis macrostachys specimens collected in the region of Diamantina Chapada (Bahia, Brazil), when subjected to the same methods of extraction and quantification, showed podophyllotoxin on leaves with a yield of 0.089 mg g −1 dried plant material (Brandão et al, 2017). Cultivated in vitro on MS medium contained 1.5% sucrose, Leptohyptis macrostachys produced 5.83 mg g −1 (Fig.…”
Section: Resultsmentioning
confidence: 93%
“…Wild Leptohyptis macrostachys specimens collected in the region of Diamantina Chapada (Bahia, Brazil), when subjected to the same methods of extraction and quantification, showed podophyllotoxin on leaves with a yield of 0.089 mg g −1 dried plant material (Brandão et al, 2017). Cultivated in vitro on MS medium contained 1.5% sucrose, Leptohyptis macrostachys produced 5.83 mg g −1 (Fig.…”
Section: Resultsmentioning
confidence: 93%
“…ex Benth. ; Eriope exaltata Harley and Oocephalus crassifolius ) ( Brandão et al, 2017 ). Moreover, recently, an ultra - high - performance liquid chromatography - photodiode array - high resolution electrospray ionization tandem mass spectrometry (UHPLC - PDA - HRESI - MS/MS) method, aiming at to dereplicate podophyllotoxin-type lignans in Condea verticillata (syn.…”
Section: Phytochemistrymentioning
confidence: 99%
“…These properties have made Podophyllum a commercially important crude drug, which has been subjected to overexploitation of the primary source plants, P. peltatum and P. emodi , currently considered as endangered species. In this context, the discovery of some members of the mint family (Lamiaceae) as potential sources of podophyllotoxin provide an alternative for the harvest and exploitation of wild populations of medicinal plants, especially among species of the genera belonging to the subtribe Hyptidinae (tribe Ocimeae) …”
Section: Introductionmentioning
confidence: 99%
“…In this context, the discovery of some members of the mint family (Lamiaceae) as potential sources of podophyllotoxin 4 provide an alternative for the harvest and exploitation of wild populations of medicinal plants, especially among species of the genera belonging to the subtribe Hyptidinae (tribe Ocimeae). 5 Hyptis verticillata Jacq. (wild bushmint or John Charles herb) is a traditional remedy known by the rural population of Mexico as "hierba martina", and its employment goes back to the ancient Mesoamerican civilisations (Supporting Information, Figure S1).…”
Section: Introductionmentioning
confidence: 99%
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