Determination of taxane concentrations in Taxus canadensis clippings using high performance liquid chromatographic analysis with an internal standard

Cass, Brian; Scott, Donald S.; Legge, Raymond L.

doi:10.1002/(sici)1099-1565(199903/04)10:2<88::aid-pca440>3.0.co;2-q

Cited by 7 publications

(2 citation statements)

References 17 publications

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“…Today, the analysis of Taxus ingredients is performed mostly by high performance liquid chromatography (HPLC) using photodiode array (PDA) detection [12][13][14][15][16][17][18][19][20][21][22][23][24][25] and mass spectrometry (MS, MS/MS, laser desorption/ionisation) detection. 10,21,[25][26][27][28][29][30][31] Besides nuclear magnetic resonance (NMR) 32,33 and fluorescence 34 detection was described.…”

Section: Introductionmentioning

confidence: 99%

Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC‐MS/MS

Siegle

Pietsch

2018

Phytochemical Analysis

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Section: Introductionmentioning

confidence: 99%

Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC‐MS/MS

Siegle

Pietsch

2018

Phytochemical Analysis

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“…Since 2005, yew has primarily been harvested from Crown land. From 2006 to 2008, only small amounts (20 000 to 50 000 kg) of yew biomass were harvested probably because PAC is stable in dry yew (Cass et al 1999), and a surplus existed. As that surplus dried up, demand for yew in Ontario surged, so in 2009 about 280 000 kg of yew biomass was harvested (K. Scott 3 , personal communication, 2010).…”

Section: Introductionmentioning

confidence: 99%

Establishing a sustainable harvest for canada yew (Taxus canadensis marsh.) in Ontario

Noland

Rich

Packalen

2011

The Forestry Chronicle

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In 2003, commercial harvest of Canada yew (Taxus canadensis Marsh.) in Ontario began-but without a sustainable harvest policy. In 2005, we began to determine the sustainability of three harvest intensity treatments at three sites in central Ontario. Harvest treatments were labelled control (no initial harvest), light (two-year-old shoots removed), moderate (three-year-old shoots removed), and severe (seven-year-old shoots removed). We also looked at effects of harvest season and light levels on shoot regrowth. After three and four years, severe-harvest plants yielded less than half the biomass of the initial harvest, while biomass from moderate-harvest plants was about equal to the initial. Biomass from light-harvest plants generally increased. Moderate light levels stimulated more first-year regrowth in all plants than low light levels did but increased only Year 2 regrowth in severe-harvest plants. Spring harvest reduced first-year regrowth only. Comparing biomass of moderate-harvest plants after three or four years with initial moderate-harvest biomass suggested similar growth rate across time periods. Our results concur with Canada Yew Association sustainable harvest guidelines: Moderately harvesting three-year-old shoots plus allowing four years of regrowth before reharvest ensures sustainable harvest, at least through one harvest cycle.Key words: ground hemlock, eastern yew, sustainable commercial harvest, wild harvest résumé La récolte commerciale de l'if du Canada (Taxus canadensis Marsh.) a débuté en 2003 en Ontario, sans qu'une politique de récolte durable n'ait été établie. En 2005, nous avons tenté de déterminer la durabilité pour trois traitements d'intensité différente de récolte sur trois stations situées dans le centre de l'Ontario. Les traitements de récolte ont été appelés témoin (pas de récolte initiale), léger (coupe de la pousse de deux ans), modéré (coupe de la pousse de trois ans) et sévère (coupe de la pousse de sept ans). Nous avons étudié également les effets de la saison de la coupe et du niveau de luminosité sur la repousse de la tige. Après trois et quatre ans, les plants coupés sévèrement affichaient un rendement en biomasse de moins de la moitié de celle tirée de la récolte initiale, tandis que la biomasse des plants coupés modérément était presqu' égale à celle initialement présente. La biomasse des plants coupés légèrement avait généralement augmenté. Les niveaux modérés de luminosité ont stimulé une repousse plus importante par rapport aux niveaux réduits de luminosité chez tous les plants la première année, mais seulement chez les plants coupés sévèrement la deuxième année. La récolte effectuée au printemps a réduit la croissance de la repousse seulement la première année. La comparaison de la biomasse des plants coupés modérément après trois ou quatre années par rapport à la biomasse initiale des plants coupés modéré-ment laissent entrevoir un taux de croissance similaire au cours des années. Nos résultats sont en accord avec les directives de récolte durable de l' Ass...

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Chemical Studies on Taxus canadensis

Qin

Wang

et al. 2013

Chemistry & Biodiversity

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A series of new taxanes, 1-93, have been isolated, together with 37 known taxoids including Taxol(®) (paclitaxel) and cephalomannine, from the Canadian yew, Taxus canadensis (Taxaceae) in the past 30 years. These new taxoids possess various skeletons containing 5/7/6, 6/10/6, 6/5/5/6, 6/8/6, and 6/12 ring systems and six new taxanes with four novel skeletons, i.e., a taxane with a 6/6/8/6 ring system, a taxane with a [3.3.3] propellane skeleton, three taxanes with [3.3.3] [3.4.5] dipropellane sytems, as well as a novel taxane with a unique 5/5/4/6/6/6 hexacyclic skeleton, containing a unique [3.3.2] propellane, were isolated for the first time from natural sources. It should be emphasized that 13-acetyl-9-dihydrobaccatin III, a very useful starting material for the semisynthesis of Taxol(®) and Taxotere(®) , represents the most abundant taxane in the needles of this yew tree. These findings establish the above mentioned yew tree as significantly different from the remaining species. On the other hand, some chemical modifications on the taxanes isolated from this plant were carried out.

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Determination of taxane concentrations in Taxus canadensis clippings using high performance liquid chromatographic analysis with an internal standard

Cited by 7 publications

References 17 publications

Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC‐MS/MS

Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC‐MS/MS

Establishing a sustainable harvest for canada yew (Taxus canadensis marsh.) in Ontario

Chemical Studies on Taxus canadensis

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