Water pollution is caused by harmful chemicals, so that the use value of water is reduced or lost. Heavy metal pollution, especially mercury ion pollution, is becoming more and more serious. The purpose of this article is to study the possibility of crayfish antennae potential monitoring of water Hg^2+ pollution. The current situation of water pollution and the experimental principles of this paper are briefly introduced through literature research and investigation, and the effect of different concentrations of mercury ions on the release of the tentacle potential of Kjeldahl with a body weight of 15g was analyzed experimentally. The results showed that the solution of 10 ppb mercury ion concentration had the most obvious inhibition on the release of tentacle potential of crawfish, with a slope of -0.1438. Followed by a mercury ion solution with a concentration of 1 ppb, the slope reached -0.0842. As a whole, the higher the concentration of mercury ions in the solution, the stronger the inhibitory effect on the release of antennae potential of crawfish. The method of monitoring the water body of the crawfish antennae potential has the possibility of application. However, under actual circumstances, the ions in the solution are diverse and extremely rich. It is difficult to ensure that other ions have no effect on the release of tentacle potential of crawfish. The experiments in this article have only been conducted on inorganic mercury ions. In fact, organic mercury still exists in water pollution. Organic pollution cannot be ignored either, and further research is needed.