Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15

Dahal, Ram Hari; Nguyen, Tuan Manh; Shim, Dong Seop; Kim, Joon‐Young; Lee, Jangyul; Kim, Jaisoo

doi:10.3390/antiox9040278

Cited by 12 publications

(9 citation statements)

References 73 publications

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“…PL exerted an anti-wrinkling effect through increasing type I collagen level by decreasing MMP 1, 2, 9 expressions relating to (JNK, p38)/(c-Fos, c-Jun) signaling pathway in NHDF cells, and exerted an anti-melanogenesis effect through suppressing melanogenic enzymes activity and/or expressions relating to PKA/CREB/MITF signaling pathway in B16F10 cells. Previous studies have shown that compounds acting as MMPs and melanogenic enzymes inhibitors could be useful as anti-photoaging (anti-wrinkling and whitening) agents for the formulation of cosmetic products [ 85 , 86 , 87 ]. Therefore, PL may be used as a potential active ingredient in anti-photoaging (anti-wrinkling and whitening) cosmetics.…”

Section: Discussionmentioning

confidence: 99%

Heat-Killed Lacticaseibacillus paracasei Ameliorated UVB-Induced Oxidative Damage and Photoaging and Its Underlying Mechanisms

Zhang

Song

et al. 2022

Antioxidants

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Ultraviolet B (UVB) radiation is a major environmental causative factor of skin oxidative damage and photoaging. Lacticaseibacillus paracasei is a well-known probiotic strain that can regulate skin health. The present study investigated the effects of heat-killed Lacticaseibacillus paracasei (PL) on UVB linked oxidative damage and photoaging in skin cells (Normal human dermal fibroblast (NHDF) cells and B16F10 murine melanoma cells). Results demonstrated that: (1) PL prevented UVB-induced cytotoxicity relating to decreased DNA damage in NHDF and B16F10 cells; (2) PL alleviated UVB-induced oxidative damage through increasing GSH content, as well as antioxidant enzyme activities and mRNA levels (except MnSOD activity and mRNA levels as well as CAT mRNA level) relating to the activation of Sirt1/PGC-1α/Nrf2 signaling in NHDF cells; (3) PL attenuated UVB-induced photoaging was noticed with a decrease in the percentage of SA-β-gal positive cells in NHDF cells model. Moreover, PL attenuated UVB-induced photoaging through exerting an anti-wrinkling effect by enhancing the type I collagen level relating to the inhibition (JNK, p38)/(c-Fos, c-Jun) of signaling in NHDF cells, and exerting an anti-melanogenic effect by suppressing tyrosinase and TYRP-1 activity and/or expressions relating to the inhibition of PKA/CREB/MITF signaling in B16F10 cells. In conclusion, PL could ameliorate UVB-induced oxidative damage and photoaging. Therefore, PL may be a potential antioxidant and anti-photoaging active ingredient for the cosmetic industry.

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Section: Discussionmentioning

confidence: 99%

Heat-Killed Lacticaseibacillus paracasei Ameliorated UVB-Induced Oxidative Damage and Photoaging and Its Underlying Mechanisms

Zhang

Song

et al. 2022

Antioxidants

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“…100 μL of 0.1% DPPH solution was added to 100 μL of different concentrations (100, 80, 60, 40, 20, 10 μg/mL) of microbial extracts in a 96‐well microtiter plate. The plates were incubated at room temperature for 30 minutes in the dark, and the optical density was measured using a spectrophotometer at 515 nm (Dahal et al, 2020 ). The absorbance of the DPPH was noted as control (no extract/standard) and ascorbic acid was used as a positive control.…”

Section: Methodsmentioning

confidence: 99%

Isolation and identification of endophytic actinobacteria from Iris persica and Echium amoenum plants and investigation of their effects on germination and growth of wheat plant

Oloumi

Khaleghi

Dalvand

2023

Food Science & Nutrition

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Plant biotechnology helps to develop different types of new products with increased resistance to disease, greater tolerance to drought and salt stress, and better nutritional value. The interaction of plants and microorganisms will play a significant role to achieve this purpose. The aims of this study were to isolate endophyte Actinobacteria strains of some medicinal plants and the investigation of their bioactive potential. 15 Actinobacteria strains were selectively isolated from Persian iris and Echium amoenum plants, and then their belonging to Actinobacteria phylum was confirmed using an Actinobacteria‐specific primer pair. The antioxidant activity of the crude extract obtained from the isolated strains was investigated based on DPPH method. Investigating the antioxidant activity of the crude extract showed that at a concentration of 100 μg/mL, the two strains EG1 and EG2 had 71% and 78% antioxidant activity, respectively. According to the phylogeny studies, it was determined that two strains belonged to the Streptomyces genus. The effect of supernatant achieved from selected endophytic strain on 35‐day wheat plants showed that the supernatant considerably promotes root and shoot growth and chlorophyll content under salinity stress (150 mM NaCl). In general, it can be concluded strains that live symbiotically with medicinal plants are rich sources of bioactive compounds. Therefore, identification of the bioactive compounds in the extract of isolated Actinobacteria from medicinal plants and further studies on their metabolism are suggested.

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“…Supplementary Table S1 shows how the test reaction mixture was prepared. The reaction was incubated at 37°C for 30 min in 96-well plates ( Dahal et al, 2020 ). Ascorbic acid (vitamin C) was used as a positive control.…”

Section: Methodsmentioning

confidence: 99%

“…Microorganisms can provide a high fluence of natural bioactive molecules for food and nutraceutical applications as they can be cultivated under controlled conditions at a much faster rate than plants ( Chandra et al, 2020 ). Microbial antioxidant systems play a significant role in maintaining the cellular redox balance and protecting against oxidative stress caused by reactive oxygen species (ROS) and reactive nitrogen species (RNS; Dahal et al, 2020 ). The defense mechanisms include enzymatic and nonenzymatic antioxidant systems such as those involving superoxide dismutase, catalase, glutathione, and thioredoxin.…”

Section: Introductionmentioning

confidence: 99%

Genome insight and probiotic potential of three novel species of the genus Corynebacterium

et al. 2023

Self Cite

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Three bacterial strains, B5-R-101T, TA-R-1T, and BL-R-1T, were isolated from the feces of a healthy Korean individual. Cells of these strains were Gram-stain-positive, facultatively anaerobic, oxidase-negative, catalase-positive, rod-shaped, and non-motile. They were able to grow within a temperature range of 10–42°C (optimum, 32–37°C), at a pH range of 2.0–10.0 (optimum, pH 5.5–8.0), and at NaCl concentration of 0.5–10.5% (w/v). All the three strains exhibited 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities ranging from 58 ± 1.62 to 79 ± 1.46% (% inhibition). These strains survived in lower pH (2.0) and in 0.3% bile salt concentration for 4 h. They did not show hemolytic activity and exhibited antimicrobial activity against pathogenic bacteria, such as Escherichia coli, Acinetobacter baumannii, Staphylococcus aureus, and Salmonella enterica. The genomic analysis presented no significant concerns regarding antibiotic resistance or virulence gene content, indicating these strains could be potential probiotic candidates. Phylogenetic analysis showed that they belonged to the genus Corynebacterium, with 98.5–99.0% 16S rRNA gene sequence similarities to other members of the genus. Their major polar lipids were diphosphatidylglycerol and phosphatidylglycerol. The abundant cellular fatty acids were C16:0, C18:1ω9c, and anteiso-C19:0. Genomic analysis of these isolates revealed the presence of genes necessary for their survival and growth in the gut environment, such as multi-subunit ATPases, stress response genes, extracellular polymeric substance biosynthesis genes, and antibacterial genes. Furthermore, the genome of each strain possessed biosynthetic gene clusters with antioxidant and antimicrobial potentials, including terpenes, saccharides, polyketides, post-translationally modified peptides (RIPPs), and non-ribosomal peptides (NRPs). In silico DNA–DNA hybridization (dDDH) and average nucleotide identity (ANI) values were lower than the thresholds to distinguish novel species. Based on phenotypic, genomic, phylogenomic, and phylogenetic analysis, these potential probiotic strains represent novel species within the genus Corynebacterium, for which the names Corynebacterium intestinale sp. nov. (type strain B5-R-101T = CGMCC 1.19408T = KCTC 49761T), Corynebacterium stercoris sp. nov. (type strain TA-R-1T = CGMCC 1.60014T = KCTC 49742T), and Corynebacterium faecium sp. nov. (type strain BL-R-1T = KCTC 49735T = TBRC 17331T) are proposed.

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Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15

Cited by 12 publications

References 73 publications

Heat-Killed Lacticaseibacillus paracasei Ameliorated UVB-Induced Oxidative Damage and Photoaging and Its Underlying Mechanisms

Heat-Killed Lacticaseibacillus paracasei Ameliorated UVB-Induced Oxidative Damage and Photoaging and Its Underlying Mechanisms

Isolation and identification of endophytic actinobacteria from Iris persica and Echium amoenum plants and investigation of their effects on germination and growth of wheat plant

Genome insight and probiotic potential of three novel species of the genus Corynebacterium

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