2016
DOI: 10.22159/ijpps.2016v8i12.15108
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Development of Nanoemulsion Containing Pelargonium Graveolens Oil: Characterization and Stability Study

Abstract: Objective: To develop, characterize and evaluate the stability of nanoemulsions containing geranium oil (NEG) at different temperatures (4 °C, 25 °C and 45 °C) for 90 d. Methods:The quantification of oil in the nanostructure was performed by gas chromatography-mass spectrometry (GC-MS). The NEG was prepared in Ultra-Turrex and characterized by determining the particle size, polydispersity indices and pH. The thermo gravimetric analysis (TGA), differential scanning calorimetry (DSC) and transmission electron mi… Show more

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Cited by 15 publications
(10 citation statements)
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“…There are two methods to make nanoemulsion, low-energy and high-energy methods. Sari et al (2018) have been successfully made nanoemulsion by spontaneous emulsification method (low energy) with 5% red palm olein with 40% surfactant Tween 80 and 20% cosurfactant sorbitol [15] while another study suggests that the use of Ultra-Turrax (high energy) is a good strategy to prepare nanoemulsion [16].…”
Section: Discussionmentioning
confidence: 99%
“…There are two methods to make nanoemulsion, low-energy and high-energy methods. Sari et al (2018) have been successfully made nanoemulsion by spontaneous emulsification method (low energy) with 5% red palm olein with 40% surfactant Tween 80 and 20% cosurfactant sorbitol [15] while another study suggests that the use of Ultra-Turrax (high energy) is a good strategy to prepare nanoemulsion [16].…”
Section: Discussionmentioning
confidence: 99%
“…Temperature modification during storage can cause a decrease in the effectiveness of surfactants so that oil droplets tend to close together and eventually produce larger droplets. Globule size distribution is an important characteristic of the nanoemulsion system, as it may affect drug release and stability of the preparation [16,17].…”
Section: Discussionmentioning
confidence: 99%
“…The ζ-potential is correlated to the electrostatic repulsion and aggregation of the droplets. High positive or negative ζ-potential values (higher electrostatic repulsive forces) arrest coalescence, thus enabling stability of the emulsions [38][39][40]. The negative charges were due to the presence of free fatty acids in the surfactant [19,28].…”
Section: Discussionmentioning
confidence: 99%