Development of seasonal allergic rhinitis during the first 7 years of life

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

“…In birth cohorts, it was found that the development of pollen-induced allergic rhinitis is characterized by a marked increase in prevalence and incidence after the second year of life (1049). This study indicates that in combination with the risk of allergic predisposition, at least two seasons of pollen allergen exposure are needed before allergic rhinitis becomes clinically manifest.…”

“…The age of onset of atopy may be an important confounding factor for the development of asthma and rhinitis or rhinitis alone. In infants and very young children, lower respiratory tract symptoms often develop before nasal symptoms (1049). It is difficult to make a clear diagnosis of asthma in this age group.…”

“…However, in preschool children, in contrast to older children, allergic rhinitis occurs at the same time or later than asthma (1049).…”

Prevalencia de síntomas de rinitis alérgica y su relación con factores de riesgo en escolares de Santiago, Chile

“…El cuestionario ISAAC es fácilmente aplicable, reproducible y tiene alta especificidad para la detección de niños con atopia, al relacionar sus respuestas con pruebas cutáneas; es, por lo tanto, útil para discriminar entre niños con y sin rinitis alérgica 7,8 . Su valor predictivo positivo para atopia, en niños con síntomas, fue de 63% cuando referían rinorrea acompañado de síntomas oculares y de 67% cuando los síntomas aparecían durante perío-dos de polinización 23,27 . Redline y cols 28 proponen la aplicación de un cuestionario más detallado, que detecta la presencia de rinitis alérgica con una sensibilidad de 83% y especificidad de 61% 28 .…”

The Role of Cytokine Interleukin-2, Transcription Factor of FoxP3 in the Immunological Regulation of Allergic Rhinitis

“…Allergic rhinitis is not a dangerous disease, but its symptoms can affect a quality of life [4]. Allergic rhinitis is an unusual disease for people with the age of below 5 years old [5], with the peak incidence occurred between 17 and 22 years old [6] [7]. The impacts of allergies on the economy are increasing as well.…”