Diagnostic Aids in Oral Cancer Screening

Mozafari, Pegah Mosannen; Delavarian, Zahra; Mohtasham, Nooshin

doi:10.5772/31193

Cited by 4 publications

(2 citation statements)

References 83 publications

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“…4,5 There are many diagnostic tests for carcinoma of oral cavity, with variable limitations, implications and the indications. 6 Yet the gold standard diagnosis for the oral carcinoma is the surgical biopsy. But not all suspicious lesions should be biopsied surgically.…”

Section: Introductionmentioning

confidence: 99%

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Lugol's iodine and methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions.

Iqbal

Khan

Lohana

et al. 2023

TPMJ

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Objective: To compare Lugol’s Iodine and Methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions by taking histopathology as the gold standard. Study Design: Cross-sectional descriptive. Setting: Outpatient Department of Isra Dental College Hospital, Isra University Hyderabad. Period: January 2021 to July 2021. Material & Methods: All patients with oral premalignant lesions were selected. Methylene blue and iodine staining were used in the lesion area. The dye was applied directly with a cotton bud for 10–20 seconds, and the mouth was resigned with tap water. The dye retention pattern was evaluated by the stain retention intensity on the lesion. Incisional biopsy was performed simultaneously at that site as a gold standard. Results: Out of 60 cases, males were 49 (81.6%) and females were 11(18.3%). The mean age of males and females was 41.910.7 years and 39.87.74 years, respectively. Out of all patients, 65.0% had more than one addictive habit of mainpuri, gutka, or supari. The commonest region of oral lesions was the buccal mucosa among 61.6% of patients, followed by the alveolus in 16.6%, lips 8.3%, tongue 6.6%, and retro molar area 3.33%, while the palate and floor of the mouth were involved in 1.66% of patients. According to the diagnostic accuracy of methylene blue, the sensitivity was 89.4% and the specificity was 66.6%. According to the Lugol’s, iodine sensitivity was 83.3% and specificity was 50%. Conclusion: It has been determined that methylene blue and lugols iodine staining are the best, easy, and noninvasive screening tools to detect the early diagnosis of malignancy.

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Section: Introductionmentioning

confidence: 99%

“…But not all suspicious lesions should be biopsied surgically. 6 Many reports have showed that the oral cancer related mortality can be decreased by diagnosis and treatment at early stage of oral cancer. 1,7 Similarly, it is equally important to https://doi.org/10.29309/TPMJ/2023.30.06.7270…”

Section: Introductionmentioning

confidence: 99%

Lugol's iodine and methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions.

Iqbal

Khan

Lohana

et al. 2023

TPMJ

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Current aspects and future strategies in oral cancer research: A review

Rao¹,

Patil²,

Ghosh³

et al. 2015

JMRPS

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Oral Cancer: The Dentist's Intervention

Dekate¹,

Kumar²,

Haque³

2013

Journal of Contemporary Dentistry

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Prevention and early detection are fundamental tools in the control of the oral cancer. Until recently screening and early detection of oral cancer has been dependent on a complete visual examination. Since simple examination is subject to observer variability adjunctive screening aids have been introduced to aid in early detection of oral cancer. The present paper outlines a brief overview of techniques in improving the identification of potentially malignant changes of the oral mucosa. We conclude that further research with clear objectives is strongly required to optimize and validate these oral screening procedures.

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Diagnostic Aids in Oral Cancer Screening

Cited by 4 publications

References 83 publications

Lugol's iodine and methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions.

Lugol's iodine and methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions.

Current aspects and future strategies in oral cancer research: A review

Oral Cancer: The Dentist's Intervention

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