Dose response of alanine detectors irradiated with carbon ion beams

Abstract

The used model and its implementation show a good overall agreement for quasi-monoenergetic measurements. Deviations in depth-dose measurements are mainly attributed to uncertainties of the detector geometry implemented in the Monte Carlo simulations.

Recent improvements in the SHIELD-HIT code

“…However, when the particles hit this block, they are displaced along the z axis corresponding to the varying thickness of the ripple structure. In this paper the performance of the ripple filter is tested against an experimental depth-dose curve set (Herrmann et al 2011) acquired at the Schwerionensynchrotron accelerator at Gesellschaft für Schwerionenforschung (GSI), Darmstadt, Germany. In the experiment, a depth-dose curve was measured for a 2  2 cm 270.55MeV/u C12 beam in a water phantom with a Markus ionization chamber by PTW, Freiburg, Germany, using a 3 mm polymethyl methacrylate (PMMA) ripple filter described in Weber and Kraft (1999).…”

“…Figure 1 shows the total dose from a SHIELD-HIT10A simulation of a 270.55 MeV/u 12 C beam, widened with a 3 mm ripple filter. This is compared with an experimental depth-dose curve acquired at GSI (Herrmann et al 2011), as described Figure 1. Absolute depth-dose curve from a 270.55 MeV/u 12 C beam in water (r  1 g/cm 3 ), measured in a cylinder with a radius of 2.65 mm in slices of 0.1 mm.…”

Study of the response of phenol compounds exposed to thermal neutrons beams for Electron Paramagnetic Resonance dosimetry

“…The EPR dosimetric method has many advantages such as simple and rapid dose evaluation, the readout procedure is non-destructive, linear response of many organic and inorganic compounds (Regulla, 2005;Ciesielski et al, 2011;Gustafsson et al, 2005;Wieser, 2012;Longo et al, 2010;Fattibene et al, 2011Fattibene et al, , 2014Lund et al, 2002;Guidelli and Baffa, 2014;Parlato et al, 2007;Marrale et al, 2007aMarrale et al, ,b, 2008bMarrale et al, , 2009bMarrale et al, ,a, 2011bMarrale et al, ,c,a, 2012bMarrale et al, , 2014d2013a). EPR detectors show a behavior that suggests possible applications for various kinds of beams used for radiation therapy (Herrmann et al, 2011). Nowadays, the most widely used organic compound as a dosimeter is the alanine (Baffa and Kinoshita, 2014;Marrale et al, 2007aMarrale et al, ,b, 2008bTrompier et al, 2009).…”

Dosimetry for electron Intra-Operative RadioTherapy: Comparison of output factors obtained through alanine/EPR pellets, ionization chamber and Monte Carlo-GEANT4 simulations for IORT mobile dedicate accelerator

“…These features allowed alanine to be classified as a reference standard dosimetry system by the IAEA for the measurement of high doses [22]. EPR detectors show a behavior that suggest a possible extension of their use also in hadrontherapy with protons, carbon ions [23,24] and neutrons [17,19,[25][26][27][28][29][30][31]. Alanine/EPR dosimetry is suitable for IORT dosimetry because alanine response has found to be independent of the dose rate even for the high dose rates used in this radiotherapeutic technique [7].…”