Dosimetry for electron Intra-Operative RadioTherapy: Comparison of output factors obtained through alanine/EPR pellets, ionization chamber and Monte Carlo-GEANT4 simulations for IORT mobile dedicate accelerator

Marrale, Maurizio; Longo, A.; Russo, G.; Casarino, Carlo; Candiano, G.; Gallo, Salvatore; Carlino, A.; Brai, Maria

doi:10.1016/j.nimb.2015.05.022

Cited by 22 publications

(11 citation statements)

References 43 publications

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“…[20][21][22][23] As a result, the 2003 guidelines developed by the Italian National Institute of Health (ISS, National Health Service) recommended using ferrous sulfate dosimetry, 24 as provided by the National Institute of Ionizing Radiation Metrology (INMRI, ENEA, Italy, called as "ENEA-INMRI" hereafter), or alternatively alanine dosimeters. 25,26 It was recommended that chemical dosimetry be managed by a Primary Metrological Institute or by a recognized calibration center due to the highly critical nature of these measurements. 21 Concerning ferrous sulfate dosimetry, the irradiation of the detector and its reading are not simultaneous, and the overall process, from detector ordering to the final readout, generally takes some months.…”

Section: Introductionmentioning

confidence: 99%

“…The high number of monitor units increases the measurement time and, potentially, the required thickness of the shielding barriers. 15 Since 2003, many studies 14,16,22,23,26 have been published dealing with the dosimetric issues related to NOVAC and LIAC accelerators, hence it is worthwhile reconsidering the use of ionization chambers. In this respect, the aim of this study was to validate ionization chambers for the reference dosimetry of NOVAC and LIAC by comparison with ferrous sulfate dosimetry.…”

Section: Introductionmentioning

confidence: 99%

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Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Scalchi

Ciccotelli²,

Felici³

et al. 2017

Medical Physics

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The present study confirms that parallel-plate ionization chambers can properly and accurately substitute ferrous sulphate detectors in reference dosimetry of LIAC and NOVAC mobile linear accelerators. Therefore, we hope that the most commonly used protocols for reference dosimetry in external-beam radiotherapy will be updated in order to provide guidance in the calibration of electron beams from linear accelerators dedicated to IORT, so that users may benefit from specific, authoritative and up-to-date recommendations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Scalchi

Ciccotelli²,

Felici³

et al. 2017

Medical Physics

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“…Marrale et al . compared the OF measurements by means of PTW Markus chamber, Alanine for NOVAC7 model.…”

Section: Discussionmentioning

confidence: 99%

“…LIAC ® has considerably low PRF varying from 1 to 60 Hz in contrast the conventional LINACs work between 200 and 400 Hz . Thus, LIAC ® can generate DPP of 0.1 to 5 cGy/p which are notably higher than conventional LINACs (around 0.05–0.6 cGy/p) …”

Section: Introductionmentioning

confidence: 98%

Output factors of ionization chambers and solid state detectors for mobile intraoperative radiotherapy (IORT) accelerator electron beams

Güngör

Aydin

Mustafayev

et al. 2019

J Applied Clin Med Phys

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PurposeThe electron energy characteristics of mobile intraoperative radiotherapy (IORT) accelerator LIAC ® differ from commonly used linear accelerators, thus some of the frequently used detectors can give less accurate results. The aim of this study is to evaluate the output factors (OFs) of several ionization chambers (IC) and solid state detectors (SS) for electron beam energies generated by LIAC ® and compare with the output factor of Monte Carlo model (MC) in order to determine the adequate detectors for LIAC ®.MethodsThe OFs were measured for 6, 8, 10, and 12 MeV electron energies with PTW 23343 Markus, PTW 34045 Advanced Markus, PTW 34001 Roos, IBA PPC05, IBA PPC40, IBA NACP‐02, PTW 31010 Semiflex, PTW 31021 Semiflex 3D, PTW 31014 Pinpoint, PTW 60017 Diode E, PTW 60018 Diode SRS, SNC Diode EDGE, and PTW 60019 micro Diamond detectors. Ion recombination factors (k sat) of IC were measured for all applicator sizes and OFs were corrected according to k sat. The measured OFs were compared with Monte Carlo output factors (OFMC).ResultsThe measured OFs of IBA PPC05, PTW Advanced Markus, PTW Pinpoint, PTW microDiamond, and PTW Diode E detectors are in good agreement with OFMC. The maximum deviations of IBA PPC05 OFs to OFMC are −1.6%, +1.5%, +1.5%, and +2.0%; for PTW Advanced Markus +1.0%, +1.5%, +2.0%, and +2.0%; for PTW Pinpoint +2.0%, +1.6%, +4.0%, and +2.0%; for PTW microDiamond −1.6%, +2%, +1.1%, and +1.0%; and for PTW Diode E −+1.7%, +1.7%, +1.3%, and +2.5% for 6, 8, 10, and 12 MeV, respectively. PTW Roos, PTW Markus, IBA PPC40, PTW Semiflex, PTW Semiflex 3D, SNC Diode Edge measured OFs with a maximum deviation of +5.6%, +4.5%, +5.6%, +8.1%, +4.8%, and +9.6% with respect to OFMC, while PTW Diode SRS and IBA NACP‐02 were the least accurate (with highest deviations −37.1% and −18.0%, respectively).ConclusionThe OFs results of solid state detectors PTW microDiamond and PTW Diode E as well as the ICs with small electrode spacing distance such as IBA PPC05, PTW Advanced Markus and PTW Pinpoint are in excellent agreement with OFMC. The measurements of the other detectors evaluated in this study are less accurate, thus they should be used with caution. Particularly, PTW Diode SRS and IBA NACP‐02 are not suitable and their use should be avoided in relative dosimetry measurements under high dose per pulsed (DPP) electron beams.

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“…In order to compensate for small disomogenities inside the samples, the standard samples read-out process consisted of four readings for each sample. Between two successive measurements the pellet is rotated by 90 around its axis in the ESR cavity [68]. For dose estimation, the difference between the maximum and the minimum of the ESR signal is used (peak to peak amplitude).…”

Section: Esr Measurementsmentioning

confidence: 99%

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

Gallo

Iacoviello²,

Bartolotta

et al. 2017

Nuclear Instruments and Methods in Physics Research Section B:

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Dosimetry for electron Intra-Operative RadioTherapy: Comparison of output factors obtained through alanine/EPR pellets, ionization chamber and Monte Carlo-GEANT4 simulations for IORT mobile dedicate accelerator

Cited by 22 publications

References 43 publications

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Output factors of ionization chambers and solid state detectors for mobile intraoperative radiotherapy (IORT) accelerator electron beams

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

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Dosimetry for electron Intra-Operative RadioTherapy: Comparison of output factors obtained through alanine/EPR pellets, ionization chamber and Monte Carlo-GEANT4 simulations for IORT mobile dedicate accelerator

Cited by 22 publications

References 43 publications

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Output factors of ionization chambers and solid state detectors for mobile intraoperative radiotherapy (IORT) accelerator electron beams

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

Contact Info

Product

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Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey

Use of parallel‐plate ionization chambers in reference dosimetry of NOVAC and LIAC^® mobile electron linear accelerators for intraoperative radiotherapy: a multi‐center survey