2012
DOI: 10.4238/2012.march.22.4
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Downregulation of hsp22 gene expression in Drosophila melanogaster from sites located near chemical plants

Abstract: ABSTRACT.A common physiological response of organisms to environmental conditions is variation in gene expression, especially true for genes encoding for heat shock proteins. In insects, this process has been examined for induced heat or cold stress. The putative longterm imprinted/acquired heat shock protein response due to unfriendly environmental conditions has been far less studied. The Drosophila melanogaster hsp22 gene, which has been extensively reviewed as being sensitive to different changing life con… Show more

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Cited by 5 publications
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“…The molecular basis underlying the role of Hsfs in stress tolerance is still not clear. Expression of Hsps as chaperones, including Hsp18.2 and Hsp70, protects cells against injuries associated with various stressors (Simões-Araújo et al, 2003;de Azevedo et al, 2012;Magdalena et al 2012). On the other hand, HsfA1a can bind various promoter targets that are not limited to classical Hsp genes and also include other genes (Guo et al, 2008), implying a broad physiological basis for the stress tolerance role of HsfA1a.…”
Section: A B C Discussionmentioning
confidence: 99%
“…The molecular basis underlying the role of Hsfs in stress tolerance is still not clear. Expression of Hsps as chaperones, including Hsp18.2 and Hsp70, protects cells against injuries associated with various stressors (Simões-Araújo et al, 2003;de Azevedo et al, 2012;Magdalena et al 2012). On the other hand, HsfA1a can bind various promoter targets that are not limited to classical Hsp genes and also include other genes (Guo et al, 2008), implying a broad physiological basis for the stress tolerance role of HsfA1a.…”
Section: A B C Discussionmentioning
confidence: 99%