Earthquake early warning (EEW) not only improves resilience against the risk of earthquake disasters, but also provides new insights into seismological processes. The Finite-Fault Rupture Detector (FinDer) is an efficient algorithm to retrieve line-source models of an ongoing earthquake from seismic real-time data. In this study, we test the performance of FinDer in the Sichuan-Yunnan region (98.5oE–106.0oE, 22.0oN–34.0oN) of China for two datasets: the first consists of seismic broadband and strong-motion records of 58 earthquakes with 5.0 ≤ MS ≤ 8.0; the second comprises additional waveform simulations at sites where new stations will be deployed in the near future. We utilize observed waveforms to optimize the simulation approach to generate ground-motion time series. For both datasets the resulting FinDer line-source models agree well with the reported epicenters, focal mechanisms, and finite-source models, while they are computed faster compared to what traditional methods can achieve. Based on these outputs, we determine a theoretical relation that can predict for which magnitudes and station densities FinDer is expected to trigger, assuming that at least three neighboring stations must have recorded accelerations of 4.6 cm/s2 or more. We find that FinDer likely triggers and sends out a report, if the average distance between the epicenter and the three closest stations, Depi, is equal or smaller than log10 (Ma + b) + c, where a = 1.91, b = 5.93, and c = 2.34 for M = MW ≥ 4.8, and c = 2.49 for M = MS ≥ 5.0, respectively. If the data used in this study had been available in real-time, 40–70% of sites experiencing seismic intensities of V-VIII (on both Chinese and MMI scales) and 20% experiencing IX-X could have been issued a warning 5–10 s before the S-wave arrives. Our offline tests provide a useful reference for the planned installation of FinDer in the nationwide EEW system of Chinese mainland.