Ecdysteroids from the Aerial Parts of Paris verticillata

Abstract

Two new ecdysteroids 14‐epi‐polypodine B (1) and 22‐oxo‐hydroxyecdysterone (2), along with nine known compounds, polypodine B (3), viticosterone E (4), 20‐hdroxyecdysone‐2‐acetate (5), 22‐oxo‐20‐hydroxyecdysone (6), 5‐hydroxyecdysone (7), pinnatasterone (8), 3‐epi‐20‐hydroxyecdysone (9), ecdysterone (10) and stachysterone B (11), were isolated from the aerial parts of Paris verticillata. The structures of all compounds were elucidated by extensive spectroscopic analysis, quantum chemical calculations and ANN‐PRA/DP4+ probability analysis. Among them, the absolute configuration of compound 1 and 2 was unambiguous determined by ECD. Also, the isolated compounds were assessed for their cytotoxic activities. Compounds 2, 3 and 7 exhibited significant cytotoxic activities against PC12, LN299 and SMCC7721 cells.

Efficiency evaluation of innovative herbal compositions with inulin

“…Pedersen), Chinese plant Cyanotis vaga, etc. have appeared on the world market [3][4][5]. Since the use of extracts obtained from the leaves and stems of medicinal plants, or plants that do not have a tradition of food use, in food products is limited (including by law), the search for food plants -new sources of phytoecdysteroids is of interest.…”