Effect of heparin on proliferation mesencymal stem cell

Susanto, Agus; Putera, Bayu Winata; Wijaya, Andi Yasmin; Muhtadi, ‪Ahmad

doi:10.1016/j.jcyt.2019.03.515

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, it was found that the effects of heparin on healthy proliferating cells and tissues depended on its concentration. For example, heparin has a stimulating effect on cell proliferation at low and very low concentrations, while increased concentrations inhibit cell proliferation [14] (Fig. 1).…”

Section: The Effect Of Heparin On Mesenchemic Cells and Tissuesmentioning

confidence: 93%

Osteogenic and Angiogenic Properties of Heparin as a System for Delivery of Biomolecules for Bone Bioengineering: a Brief Critical Review

Литвинова

Yurova

Хазиахматова

et al. 2021

Biochem. Moscow Suppl. Ser. B

View full text Add to dashboard Cite

The review considers complex, controversial, and individual effects of heparin and its derivatives on the bone and circulatory systems in dependence of the dose, the state of the cells and tissues of the recipient. General data on the anticoagulant activity of heparin and its derivatives are presented; special attention is paid to the effect of heparin on mesenchymal cells and tissues and its role in angiogenesis. We also discuss the ability of heparin to bind osteogenic and angiogenic biomolecules in the context of the development of systems for their delivery and sustained controlled release and propose a schematic representation of the positive and side effects of heparin as a delivery system for biomolecules in tissue engineering.

show abstract

Section: The Effect Of Heparin On Mesenchemic Cells and Tissuesmentioning

confidence: 93%

Osteogenic and Angiogenic Properties of Heparin as a System for Delivery of Biomolecules for Bone Bioengineering: a Brief Critical Review

Литвинова

Yurova

Хазиахматова

et al. 2021

Biochem. Moscow Suppl. Ser. B

View full text Add to dashboard Cite

show abstract

“…Однако было обнаружено, что эффекты гепарина на здоровые пролиферирующие клетки и ткани зависят от его концентрации. Так, стимулирующее действие на пролиферацию клеток гепарин оказывает в низких и очень низких концентрациях, а с увеличением концентрации он тормозит клеточную пролиферацию [14] (рисунок). По данным Khan и соавт., опухолевые клетки, напротив, отвечали на гепарин усилением пролиферации и ослаблением дифференцировки через опосредованные BMP-4 сигнальные пути [15] (рисунок).…”

Section: влияние гепарина на мезенхимные клетки и тканиunclassified

Osteogenic and angiogenic properties of heparin as a system of biomolecule delivery for bone bioengineering: a brief critical review

et al. 2020

View full text Add to dashboard Cite

The review discusses the complex, ambiguous and individual effects of heparin and its derivatives on the bone and circulatory systems, in dependence of the dosage, the state of the cells and tissues of recipients. General data on the anticoagulant activity of heparin and its derivatives are presented; aspects of the effect of heparin on mesenchymal cells and tissues and its role in angiogenesis are considered in details. Particular attention is paid to the ability of heparin to bind osteogenic and angiogenic biomolecules: thus us especially important for the development of systems for their delivery and sustained controlled release. A schematic representation of the positive and side effects of heparin as a delivery system for biomolecules in tissue engineering is proposed.

show abstract

Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function

Rangasami¹,

Asawa²,

Teramura³

et al. 2023

Biomaterials Advances

View full text Add to dashboard Cite

Effect of heparin on proliferation mesencymal stem cell

Cited by 3 publications

References 0 publications

Osteogenic and Angiogenic Properties of Heparin as a System for Delivery of Biomolecules for Bone Bioengineering: a Brief Critical Review

Osteogenic and Angiogenic Properties of Heparin as a System for Delivery of Biomolecules for Bone Bioengineering: a Brief Critical Review

Osteogenic and angiogenic properties of heparin as a system of biomolecule delivery for bone bioengineering: a brief critical review

Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function

Contact Info

Product

Resources

About