Effect of herbal tea on glycemic control in patients with type 2 diabetes

Abstract

Background: Type 2 diabetes (T2D) is a significant health concern worldwide, and good glycemic control is the basis of avoiding disease progression. Herbal tea, as a convenient and effective medication method, has gained popularity among many diabetic patients. However, there are no systematic reviews or meta-analyses to evaluate the clinical efficacy of herbal tea on T2D.Methods: Four English electronic databases and 4 Chinese electronic databases were searched for randomized controlled trials (RCTs) meeting inclusion criteria; Clinical trials were searched to explore the relevant unpublished data. Fasting blood glucose and glycated hemoglobin will be measured as primary outcomes. Secondary outcomes include 2-hour postprandial blood glucose, fasting insulin, and homeostasis model assessment-insulin resistance. The heterogeneity of data will be investigated by Chi-square and I 2 test; subgroup analysis and sensitivity analysis will be conducted to explore the sources of heterogeneity; funnel plot will be used to evaluate publication bias; finally, we will use grading of recommendations assessment, development, and evaluate system method to evaluate the quality of evidence. Merging analysis of data will be performed using Rev Man 5.3 software.Results: The results will be published in a peer-reviewed journal. Conclusions:The systematic review will confirm whether herbal tea consumption is benefit to the glycemic control in patients with T2D.PROSPERO registration number: CRD42019129863.Abbreviations: 2-h PBG = 2-hour postprandial blood glucose, FBG = fasting blood glucose, FINS = fasting insulin, GRADE = grading of recommendations assessment, development, and evaluate system, HbA1C = glycated hemoglobin, HOMA-IR = homeostasis model assessment-insulin resistance, RCTs = randomized controlled trials.

Opposite Effects of F1 and F5 Fractions of Total Methanol Leaf-extract of Dialium guineense (Cesalpiniaceae) on Blood Glucose in Rat

“…The recent development of herbal medicine offers an opportunity to find molecules in plants and that may have beneficial effects on the regulation of glucose metabolism, while avoiding side effects of synthetic substances [3,4].…”