Effect of immune stress on growth performance and energy metabolism in broiler chickens

Abstract

2015)Effect of immune stress on growth performance and energy metabolism in broiler chickens, Food and Agricultural Immunology, 26:2,[194][195][196][197][198][199][200][201][202][203] This study was conducted to investigate the effects of different types of immune stress on the growth performance and energy metabolism in broiler chickens (Cobb 500). Three hundred and twenty one-day-old broilers were randomly assigned (n = 80 birds/ group) to receive one of four treatments: (1) no vaccination, (2) conventional vaccination, (3) cyclophosphamide (CPM) stress and (4) lipopolysaccharide (LPS) stress. The results demonstrated that immune stress reduced the daily feed intake, average daily weight gain, plasma renin activity, serum angiotensin II and amylase activity of jejunal digesta (P < 0.05). The body temperature of broilers increased rapidly after LPS administration on days 16, 18 and 20, but attenuated on days 37, 39 and 41. The data suggested that immune stress can negatively affect the utilisation of energy in broilers, resulting in the decreased growth performance.

The hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype

“…We found that LPS treatment had no effect on total plasma complement activity, though it compromised chick growth performance, including both overall and structural body size. Our finding regarding the growth inhibiting effect of LPS treatment is in agreement with previous studies on poultry ( Liu et al, 2015 ; Wang et al, 2015 ; Zheng et al, 2016 ). However, it is surprising that despite the evidence for avidin's involvement in regulation of tissue injury or viral transformation-induced inflammation processes ( Korpela et al, 1983 ; Elo and Korpela, 1984 ), and the fact that antimicrobial and complement-related proteins are considered some of the main innate immunity effector molecules ( Buchmann, 2014 ), we failed to observe any interactive effect of LPS treatment and egg white avidin treatment on total plasma complement activity.…”

Dietary L-theanine alleviated lipopolysaccharide-induced immunological stress in yellow-feathered broilers

“…To be specific, diet nutrients were away from growth, but toward processes associated with inflammatory immune response and synthesis of various mediators such as cytokines ( Liu et al., 2015 , Li et al., 2015b ). Besides, immunological stress easily caused intestinal structure injury ( Hu et al., 2011 , Li et al., 2015a ), intestinal digestion and absorption disorder ( Feng et al., 2012 , Liu et al., 2015 ) and body metabolic disturbance of animal ( Klasing, 2007 , Liu et al., 2014 ). In this study, dietary L-theanine significantly improved growth performance of broilers before LPS challenge, which was similar to the results described previously ( Hwang et al., 2008 , Wen et al., 2012 ).…”

“…However, various factors, such as pathogenic microorganisms, heavy vaccinations, drug abuse and other external elements in the intensive production system will attack birds to induce the loss of immune homeostasis and trigger immune stress response directly or indirectly ( Liu et al., 2015 ). Under stress, chickens may be vulnerable to suffer from enteric diseases, which will affect their intestine health and growth performance, inflicting huge financial losses to poultry production ( Yang et al., 2011 , Liu et al., 2014 ).…”

Effects of dietary enzymolysis products of wheat gluten on the growth performance, serum biochemical, immune, and antioxidant status of broilers

“…It is worth noting that the biological responses depend on dietary components. In the poultry industry, birds are often exposed to different stressful conditions, which increase the production of free radicals and limit the growth performance (Bai et al, 2017;Liu, Qin, et al, 2015;Toro, Aguilar, Bertot, Hurtado, & Nava, 2015). The antioxidant system includes natural or synthetic antioxidants enzymes (Hu et al, 2016), with T-SOD and GSH-Px being the most important of those antioxidant enzymes.…”