The adhesion of biofilm on dental prostheses is a prerequisite for the occurrence of
oral diseases.ObjectiveTo assess the antimicrobial activity and the mechanical properties of an acrylic
resin embedded with nanostructured silver vanadate (β-AgVO3).Material and MethodsThe minimum inhibitory concentration (MIC) of β-AgVO3 was studied in
relation to the species Staphylococcus aureus ATCC 25923,
Streptococcus mutans ATCC 25175, Pseudomonas
aeruginosa ATCC 27853, and Candida albicans ATCC
10231. The halo zone of inhibition method was performed in triplicate to determine
the inhibitory effect of the modified self-curing acrylic resin Dencor Lay -
Clássico®. The surface hardness and compressive strength were
examined. The specimens were prepared according to the percentage of
β-AgVO3 (0%-control, 0.5%, 1%, 2.5%, 5%, and 10%), with a sample
size of 9x2 mm for surface hardness and antimicrobial activity tests, and 8x4 mm
for the compression test. The values of the microbiologic analysis were compared
and evaluated using the Kruskal-Wallis test (α=0.05); the mechanical analysis used
the Shapiro-Wilk's tests, Levene's test, ANOVA (one-way), and Tukey's test
(α=0.05).ResultsThe addition of 10% β-AgVO3 promoted antimicrobial activity against all
strains. The antimicrobial effect was observed at a minimum concentration of 1%
for P. aeruginosa, 2.5% for S. aureus, 5% for
C. albicans, and 10% for S. mutans. Surface
hardness and compressive strength increased significantly with the addition of
0.5% β-AgVO3 (p<0.05). Higher rates of the nanomaterial did not
alter the mechanical properties of the resin in comparison with the control group
(p>0.05).ConclusionsThe incorporation of β-AgVO3 has the potential to promote antimicrobial
activity in the acrylic resin. At reduced rates, it improves the mechanical
properties, and, at higher rates, it does not promote changes in the control.