2013
DOI: 10.1007/s40011-013-0157-y
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Effect of Sub-Acute Toxicity of Bifenthrin on Antioxidant status and Hematology After its Oral Exposure in Goats

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Cited by 13 publications
(13 citation statements)
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“…Reduced levels of glutathione in several tissues have been reported with various pyrethroids (Prasanthi, Muralidharan, and Rajani 2005;Dubey, Raina, and Khan 2012;Khan et al 2013b;Dar et al 2013). The endogenous availability of glutathione at the target site might be a limiting factor for GPx and GST catalyzed-free-radical detoxification (Raina et al 2009;Khan et al 2013b). In this study, reduced glutathione (GSH) levels in brain tissue were not determined, although, levels of GSH decreased in blood (Dar et al 2013).…”
Section: Discussionmentioning
confidence: 77%
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“…Reduced levels of glutathione in several tissues have been reported with various pyrethroids (Prasanthi, Muralidharan, and Rajani 2005;Dubey, Raina, and Khan 2012;Khan et al 2013b;Dar et al 2013). The endogenous availability of glutathione at the target site might be a limiting factor for GPx and GST catalyzed-free-radical detoxification (Raina et al 2009;Khan et al 2013b). In this study, reduced glutathione (GSH) levels in brain tissue were not determined, although, levels of GSH decreased in blood (Dar et al 2013).…”
Section: Discussionmentioning
confidence: 77%
“…Decreased activity of SOD and CAT has been reported in rats exposed to pyrethroids (Eraslan, Kanbur, and Silici 2008;Hussein, Elnaggar, and Al-Dailamy 2012). Significant decrease in the activity of GPx (Raina et al 2009;Dubey, Raina, and Khan 2012;Dubey, Khan, and Raina 2013;Khan et al 2013b;Dar et al 2013) and GST (Singh, Saxena, and Sharma 2009;Dar et al 2013) has also been reported with several pyrethroids in various tissues. GSTs bind with varying affinities to an array of hydrophobic compounds such as polycyclic aromatic hydrocarbons and other xenobiotics like pyrethroids (Singh, Saxena, and Sharma 2009).…”
Section: Discussionmentioning
confidence: 96%
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