Effects of Exercise on Plasma and Liver Lipids of Rats

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

1980

SummaryThe effect of voluntary exercise on serum lipoprotein distributions, lecitin: cholesterol acryltransferase (LCAT) activity and serum electrophoretic patterns of mice fed different levels of dietary protein were investigated. Serum cholesterol of all exercise groups (E) showed a lower value than that of the non-exercise groups (NE). Ratios of cholesteryl ester to serum total cholesterol tended to be higher in the exercise groups than in non exercise groups. High density lipoprotein(HDL)-cholesterol/serum total cholesterol ratios and HDL-cholesterol/low density lipoprotein(LDL) cholesterol ratios were increased by voluntary exercise. With regard to low density lipoprotein cholesterol levels, there were significant differ ences between 20% E and 20% NE groups, 4% E and 4% NE groups, respectively. It was found that HDL fractions in serum lipoprotein patterns of exercise groups differed from those of non-exercise groups. This seemed to be prominent in low protein diet groups. LCAT activity showed decreasing values as dietary protein levels decreased and its activity was raised by voluntary exercise in all groups.

Section: Discussionmentioning

confidence: 99%

Effect of voluntary exercise and dietary protein levels on serum lipoprotein distributions and lecithin: cholesterol acyltransferase (LCAT) activity of mice.

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

1980

“…Many investigations concerning the effects of exercise on serum and liver lipids have been reported from a preventive point of view, for instance hyperlipemia and atherosclerosis, with regard to the relationship between exercise and health (6,7,26,27). MORRIS and HEADY (8) suggested that physical activity in work is associated with a lower incidence of coronary heart disease in middle-aged men.…”

mentioning

confidence: 99%

“…Namely, decreasing the level of dietary protein results in increased plasma and liver cholesterol and liver fat levels (9,30). So far it is known that exercise causes a reduction in the level of plasma lipids (6,7). But there are few reports concerned with the effect of a combination of exercise and dietary protein levels on plasma and liver lipids.…”

mentioning

confidence: 99%

Effect of the combination of voluntary exercise and dietary protein levels on the deposition of glycogen, liver and serum lipids in mice.

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

1979

SummaryThe effects of voluntary exercise on the growth, glycogen of muscle and lipid contents of the liver and serum of mice fed different levels of dietary protein were investigated. In both the exercise and non-exercise groups, body weight gains were significantly greater in the 20% and 30% protein diet groups than in the 6% and 4% protein diet groups. After 6 weeks of age, it was shown that the amount of voluntary exercise by the 6% and 4% protein diet groups was greater than that by the 20% and 30% protein diet groups. As for hematological status, the raising of hemoglobin levels due to increasing dietary protein levels was further exaggerated by voluntary exercise. Hematocrit values rose with the increase in dietary protein levels. However the effect of exercise on hematocrit values was not clear. Liver glycogen levels, which were elevated with the increase in dietary protein levels, rose further due to exercise, though no changes were observed in muscle glycogen due to dietary protein levels and exercise. The lipid contents of the liver in all groups tended to be lower in exercise groups compared with non-exercise groups and it was observed that the high levels of dietary protein depressed the increase in liver lipids. Liver triglyceride levels of all groups fed the dietary protein levels except for the 20% casein diet group decreased due to voluntary exercise, and liver triglyceride levels were also lowered as dietary protein levels increased. The levels of serum triglyceride of all groups decreased due to voluntary exercise. This phenomenon was most remarkable in rats fed a 6% casein diet. The tendency for serum cholesterol levels to decrease due to increasing dietary levels of protein was further intensified by voluntary exercise. However it was not further influenced by voluntary exercise in the 4% casein diet group.

“…Previously, it has been found that the body weight gains of rats are decreased by training (5,6). In the present study, the 20% E group had smaller body weight gains than the nonexercise group.…”

Section: Discussionmentioning

confidence: 99%

Effect of voluntary exercise on physiological function and feeding behavior of mice on a 20% casein diet or a 10% casein diet.

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

1979

SummaryThe effects of voluntary exercise on growth and food intake, body composition, organ weight, and fatty acid composition of adipose tissue of mice fed on a 20% casein diet or a 10% casein diet were examined. The weight gain was greater for the 20% casein nonexercise group (20% NE) than that for the 20% casein exercise group (20% E), 10% casein exercise group (10% E) and 10% casein nonexercise group (10% NE). There were no significant differences between the groups except the 20% NE. In 20% E and 10% E, body fats decreased markedly. On the other hand, a very high ratio of protein was present in the body composition of both groups. In the 20% and 10% casein diet groups, food intake was increased by voluntary exercise, but there was no significant difference between 10% E and 10% NE except occasional periods during these experiments. After 6 weeks of age, 10% E had a tendency to undertake more voluntary exercise than 20% E, though the difference was not statistically significant. Development of the heart and gastrocnemius muscles was accelerated by voluntary exercise and epididymal fat tissue was markedly decreased. Keywords voluntary exercise, low protein diet, growth, food intake, calorie intake, body composition In recent years, it has been emphasized that physical exercises are necessary to maintain physical fitness and to prevent obesity or senescence. It seems that the main factors affecting physical fitness and health are dietary regimen and physical exercise. The problem of the relationship between nutrition and health or life-span has been studied by many researchers among whom the studies of MACCAY et al . (1) and BERG and SIMMS(2) were excellent. Nevertheless, there are still many uncertainties with regard to the relationship between physical exercise and longevity 23 24